Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.66 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.62 |
| ▸ | RARB | P10826 | 10/20 | 0.60 |
| ▸ | RARA | P10276 | 2/20 | 0.60 |
| ▸ | RARG | P13631 | 1/20 | 0.60 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 2/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.55 |
| ▸ | TACR2 | P21452 | 2/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SHBG | P04278 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11135668 | 0.93 | RARB (0.68) | PPARAKAT8RARBRARARARG | |
| SCHEMBL9247776 | 0.93 | RARB (0.68) | PPARAKAT8RARBRARARARG | |
| SCHEMBL9155410 | 0.93 | RARB (0.68) | PPARAKAT8RARBRARARARG | |
| SCHEMBL9511147 | 0.92 | RARB (0.67) | PPARAKAT8RARBRARARARG | |
| SCHEMBL4908288 | 0.92 | RARB (0.66) | PPARAKAT8RARBRARARARG | |
| SCHEMBL9755592 | 0.90 | RARB (0.65) | PPARAKAT8RARBRARARARG | |
| SCHEMBL5666124 | 0.90 | RARB (0.64) | PPARAKAT8RARBRARARARG | |
| SCHEMBL5665865 | 0.90 | RARB (0.64) | PPARAKAT8RARBRARARARG | |
| SCHEMBL9842588 | 0.89 | RARB (0.63) | PPARAKAT8RARBRARARARG | |
| SCHEMBL18038416 | 0.89 | PPARA (0.65) | PPARAKAT8RARBRARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110216273-A1 | MESOGEN-CONTAINING COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2011-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110216273-A1 | MESOGEN-CONTAINING COMPOUNDS | BMP2, MYOC, RARG | PPARA 1028/4885KAT8 4083/4885RARB 38/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.