Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | AGXT | P21549 | 2/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 5/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6478581 | 0.77 | IDO1 (0.39) | IDO1CYP1A2CYP2A6TAAR1AGXT | |
| SCHEMBL25393873 | 0.75 | THRA (0.42) | IDO1CYP1A2CYP2A6TAAR1AGXT | |
| SCHEMBL1821550 | 0.75 | IDO1 (0.46) | IDO1CYP1A2CYP2A6TAAR1AGXT | |
| SCHEMBL19451469 | 0.75 | IDO1 (0.46) | IDO1CYP1A2CYP2A6TAAR1AGXT | |
| SCHEMBL14047948 | 0.73 | ESR1 (0.44) | IDO1CYP1A2CYP2A6TAAR1AGXT | |
| SCHEMBL28275285 | 0.73 | IDO1 (0.44) | IDO1CYP1A2CYP2A6TAAR1AGXT | |
| SCHEMBL19669538 | 0.73 | IDO1 (0.44) | IDO1CYP1A2CYP2A6TAAR1AGXT | |
| SCHEMBL23719180 | 0.71 | IDO1 (0.42) | IDO1CYP1A2CYP2A6TAAR1AGXT | |
| SCHEMBL5754624 | 0.71 | IDO1 (0.42) | IDO1CYP1A2CYP2A6TAAR1AGXT | |
| SCHEMBL10921319 | 0.71 | ESR1 (0.39) | IDO1CYP1A2CYP2A6TAAR1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081967-A1 | MALT1 MODULATORS AND USES THEREOF | RHEOS MEDICINES, INC. (US) | 2022-04-21 | — | — | WO | disclosed |