Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28161462 | 0.80 | ALDH1A1 (0.45) | ALDH1A1ALOX15RECQLHTTCASP1 | |
| SCHEMBL325499 | 0.77 | GPR174 (0.57) | ALDH1A1ALOX15RECQLHTTCYP2C9 | |
| SCHEMBL15450456 | 0.75 | ALDH1A1 (0.52) | ALDH1A1ALOX15RECQLHTTCASP1 | |
| SCHEMBL10046483 | 0.74 | KMT2A (0.76) | ALDH1A1ALOX15HTTNPSR1GAA | |
| SCHEMBL11823279 | 0.73 | ESR2 (0.50) | ALDH1A1HTTCASP1CASP7CYP2C9 | |
| SCHEMBL15450451 | 0.70 | GPR174 (0.55) | ALDH1A1ALOX15RECQLHTTCYP2C9 | |
| SCHEMBL15450513 | 0.69 | GPR174 (0.58) | ALDH1A1ALOX15RECQLHTTCYP2C9 | |
| SCHEMBL8084149 | 0.69 | GAA (0.67) | ALDH1A1ALOX15RECQLHTTCYP2C9 | |
| SCHEMBL31238216 | 0.68 | ALDH1A1 (0.53) | ALDH1A1ALOX15RECQLCYP2C9CYP2C19 | |
| SCHEMBL13228482 | 0.67 | GAA (0.64) | ALDH1A1ALOX15RECQLHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220110942-A1 | GERM CELL NUCLEAR FACTOR LIGANDS AND METHODS OF USE THEREOF | SAINT LOUIS UNIVERSITY (US) | 2022-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220110942-A1 | GERM CELL NUCLEAR FACTOR LIGANDS AND METHODS OF USE THEREOF | NASP, ALPG, GMFG | ALDH1A1 2726/4885ALOX15 3005/4885RECQL 3708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.