Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | MITF | O75030 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23711000 | 0.92 | MAPT (0.59) | MAPTKMT2AMEN1MITFCYP1A2 | |
| SCHEMBL21651804 | 0.81 | MAPT (0.98) | MAPTKMT2AMEN1MITFPOLB | |
| SCHEMBL12793844 | 0.80 | TDP1 (0.72) | MAPTKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL21651803 | 0.79 | KDM4E (0.54) | MAPTKMT2AMEN1CYP1A2MAPK1 | |
| SCHEMBL12793858 | 0.79 | TDP1 (0.69) | MAPTKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL1096271 | 0.75 | MEN1 (0.61) | MAPTKMT2AMEN1CYP2C9MAPK1 | |
| SCHEMBL8290348 | 0.73 | MAPT (0.75) | MAPTKMT2AMEN1MITFCYP1A2 | |
| SCHEMBL1095867 | 0.73 | CNR2 (0.57) | MAPTKMT2AMEN1MITFMAPK1 | |
| SCHEMBL19392435 | 0.72 | KMT2A (1.00) | MAPTKMT2AMEN1CYP1A2CYP3A4 | |
| SCHEMBL23711014 | 0.72 | MAPT (0.81) | MAPTKMT2AMEN1MITFPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230132397-A9 | USE OF TOLL-LIKE RECEPTOR 2 (TLR-2) AGONIST FOR MODULATING HUMAN IMMUNE RESPONSE | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2023-04-27 | — | — | US | disclosed |
| US-20220118085-A9 | USE OF TOLL-LIKE RECEPTOR 2 (TLR-2) AGONIST FOR MODULATING HUMAN IMMUNE RESPONSE | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2022-04-21 | — | — | US | disclosed |
| US-9586978-B2 | Anti-viral compounds | ABBVIE INC. (US) | 2017-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220118085-A9 | USE OF TOLL-LIKE RECEPTOR 2 (TLR-2) AGONIST FOR MODULATING HUMAN IMMUNE RESPONSE | TLR2, TLR1, TLR3 | MAPT 206/4885KMT2A 2910/4885MEN1 4788/4885 |
| US-20230132397-A9 | USE OF TOLL-LIKE RECEPTOR 2 (TLR-2) AGONIST FOR MODULATING HUMAN IMMUNE RESPONSE | TLR2, TLR1, TLR3 | MAPT 206/4885KMT2A 2910/4885MEN1 4788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.