Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.68 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PRKCG | P05129 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PRKCB | P05771 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PRKCA | P17252 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Osthenol SCHEMBL51013 | 0.81 | PTGS1 (1.00) | MAOAPTGS1SRD5A1ALDH1A1MCL1 | |
| SCHEMBL29074526 | 0.80 | SRD5A1 (1.00) | MAOAPTGS1SRD5A1ALDH1A1MCL1 | |
| SCHEMBL28267385 | 0.75 | MAOA (0.65) | MAOAPTGS1SRD5A1ALDH1A1MCL1 | |
| SCHEMBL28267386 | 0.75 | MAOA (0.65) | MAOAPTGS1SRD5A1ALDH1A1MCL1 | |
| SCHEMBL30776763 | 0.74 | SRD5A1 (0.64) | MAOAPTGS1SRD5A1ALDH1A1MCL1 | |
| SCHEMBL30158338 | 0.73 | MAOA (0.78) | MAOAPTGS1SRD5A1ALDH1A1CYP3A4 | |
| SCHEMBL24075636 | 0.73 | MAOA (0.78) | MAOAPTGS1SRD5A1ALDH1A1CYP3A4 | |
| SCHEMBL9474687 | 0.72 | MAOA (0.57) | MAOAPTGS1SRD5A1ALDH1A1MCL1 | |
| SCHEMBL28217310 | 0.71 | SRD5A1 (0.59) | MAOAPTGS1SRD5A1ALDH1A1MCL1 | |
| SCHEMBL31377055 | 0.71 | MAOA (0.59) | MAOAPTGS1SRD5A1ALDH1A1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022049598-A1 | COMPOUNDS FOR THE DETECTION OF HOMOCYSTEINE AND ITS METHOD OF PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-03-10 | — | — | WO | disclosed |