Osthenol

Osthenol

SCHEMBL51013

CC(C)=CCc1c(O)ccc2ccc(=O)oc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTGS1 P23219 2/20 1.00
▸ MAOA P21397 1/20 1.00
▸ SRD5A1 P18405 1/20 0.68
▸ XPO1 O14980 2/20 0.68
▸ PTGS2 P35354 2/20 0.68
▸ ALDH1A1 P00352 2/20 0.68
▸ CYP3A4 P08684 2/20 0.68
▸ ABCB1 P08183 2/20 0.68
▸ ALOX5 P09917 1/20 0.68
▸ GABRA1 P14867 1/20 0.68
▸ GABRB2 P47870 1/20 0.68
▸ KDM4E B2RXH2 2/20 0.62
▸ CA9 Q16790 3/20 0.53
▸ PRKD3 O94806 1/20 0.51
▸ EGFR P00533 1/20 0.51
▸ LMNA P02545 1/20 0.51
▸ PRKCG P05129 1/20 0.51
▸ CYP1A2 P05177 1/20 0.51
▸ PRKCB P05771 1/20 0.51
▸ POLB P06746 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30158338 0.88 MAOA (0.78) PTGS1MAOASRD5A1XPO1PTGS2
SCHEMBL24075636 0.88 MAOA (0.78) PTGS1MAOASRD5A1XPO1PTGS2
SCHEMBL12299958 0.85 PTGS1 (0.74) PTGS1MAOASRD5A1XPO1PTGS2
SCHEMBL17194876 0.82 PTGS1 (0.70) PTGS1MAOASRD5A1XPO1PTGS2
SCHEMBL29074526 0.81 SRD5A1 (1.00) PTGS1MAOASRD5A1ALDH1A1CYP3A4
Osthole SCHEMBL50436 0.81 PTGS2 (1.00) PTGS1MAOASRD5A1XPO1PTGS2
Osthole SCHEMBL17513161 0.81 PTGS2 (1.00) PTGS1MAOASRD5A1XPO1PTGS2
Osthole SCHEMBL29595542 0.81 PTGS2 (1.00) PTGS1MAOASRD5A1XPO1PTGS2
SCHEMBL24337416 0.81 MAOA (0.68) PTGS1MAOASRD5A1XPO1PTGS2
Osthole SCHEMBL27681201 0.80 PTGS2 (0.97) PTGS1MAOASRD5A1XPO1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105555287-A Plant-based ketohexokinase inhibitors for supporting weight management ACCESS BUSINESS GROUP INT LLC 2016-05-04 — — CN claimed
EP-3010520-A1 PLANT-BASED INHIBITORS OF KETOHEXOKINASE FOR THE SUPPORT OF WEIGHT MANAGEMENT Access Business Group International LLC (US) 2016-04-27 — — EP claimed
US-20140377386-A1 PLANT-BASED INHIBITORS OF KETOHEXOKINASE FOR THE SUPPORT OF WEIGHT MANAGEMENT ACCESS BUSINESS GROUP INTERNATIONAL LLC (US) 2014-12-25 — — US claimed
WO-2014204853-A1 PLANT-BASED INHIBITORS OF KETOHEXOKINASE FOR THE SUPPORT OF WEIGHT MANAGEMENT ACCESS BUSINESS GROUP INTERNATIONAL LLC (US) 2014-12-24 — — WO claimed
WO-2009052518-A2 METHODS AND COMPOSITIONS DIRECTED TO REDUCTION OF FACIAL HAIR HIRSUTISM IN FEMALES ASPEN BENEFITS GROUP, LLC (US) 2009-04-23 — — WO claimed
CN-101362768-A Separation and purification method of monomeric compound in root of dahurain angelica UNIV PLA 2ND MILITARY MEDICAL (CN) 2009-02-11 — — CN claimed
CN-1163760-A Health food containing active component of Tianshishan ginseng and Chinese angelica plant DONG FAMING (CN) 1997-11-05 — — CN claimed
US-12507703-B2 Methods, devices and compositions for preserving human milk THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-12-30 — — US disclosed
US-20250177348-A1 Methods for Fructokinase Meditation of Alcohol Craving and Alcohol Induced Liver Disease THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE 2025-06-05 — — US disclosed
US-20250169516-A1 METHODS, DEVICES AND COMPOSITIONS FOR PRESERVING HUMAN MILK THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-05-29 — — US disclosed
US-12239142-B2 Methods, devices and compositions for preserving human milk THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2025-03-04 — — US disclosed
CN-118028256-B Cnidium hydroxylase gene CmC '2' H and application thereof 皖西学院 2025-01-21 — — CN disclosed
US-12161621-B2 Methods for fructokinase mediation of alcohol craving and alcohol induced liver disease THE REGENTS OF THE UNIVERSITY OF COLORADO 2024-12-10 — — US disclosed
US-6737084-B2 Compositions and methods for enhancing or treating female sexual response QUALILIFE 2004-05-18 — — US disclosed
WO-2004022080-A2 BUGUZHI AGENT AND COMPOSITION AND METHODS OF PREPARING AND ADMINISTERING THE SAME THE UNIVERSITY OF HONG KONG (CN) 2004-03-18 — — WO disclosed
US-20040043089-A1 Buguzhi agent and composition and methods of preparing and administering the same UNIVERSITY OF HONG KONG, THE (CN) 2004-03-04 — — US disclosed
EP-1328281-A1 COMPOSITIONS AND METHODS FOR TREATING FEMALES SEXUAL RESPONSE Qualilife Pharmaceuticals Inc. (US) 2003-07-23 — — EP disclosed
US-20020034557-A1 Compositions and methods for treating female sexual response SEMPRAE LABORATORIES, INC. 2002-03-21 — — US disclosed
WO-2002000240-A2 COMPOSITIONS AND METHODS FOR TREATING FEMALES SEXUAL RESPONSE QUALILIFE PHARMACEUTICALS INC. (US) 2002-01-03 — — WO disclosed
CN-1163760-A Health food containing active component of Tianshishan ginseng and Chinese angelica plant DONG FAMING (CN) 1997-11-05 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12161621-B2 Methods for fructokinase mediation of alcohol craving and alcohol induced liver disease KHK, GCK, FN3K PTGS1 1692/4885MAOA 1660/4885SRD5A1 3631/4885
US-12507703-B2 Methods, devices and compositions for preserving human milk LPL, CEL, LPO PTGS1 4638/4885MAOA 471/4885SRD5A1 1544/4885
US-20140377386-A1 PLANT-BASED INHIBITORS OF KETOHEXOKINASE FOR THE SUPPORT OF WEIGHT MANAGEMENT KHK, GCK, HK1 PTGS1 2524/4885MAOA 2312/4885SRD5A1 3617/4885
US-20250177348-A1 Methods for Fructokinase Meditation of Alcohol Craving and Alcohol Induced Liver Disease KHK, GCK, FN3K PTGS1 2221/4885MAOA 1165/4885SRD5A1 4297/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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