Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.34 |
| ▸ | BAZ2A | Q9UIF9 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24338940 | 0.87 | CYP4F2 (0.45) | HPGDMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL24338066 | 0.83 | PTGS2 (0.37) | HPGDMAPTKDM4EALDH1A1BAZ2B | |
| SCHEMBL3217965 | 0.78 | PDE4B (0.34) | TSHRMAPTALDH1A1KMT2ABAZ2B | |
| SCHEMBL544288 | 0.73 | KDM4E (0.41) | HPGDTSHRKDM4EALDH1A1KMT2A | |
| SCHEMBL1665456 | 0.73 | APOBEC3A (0.46) | MAPTKDM4EALDH1A1BAZ2BBAZ2A | |
| SCHEMBL3459890 | 0.72 | ADORA3 (0.48) | MAPTKDM4EKMT2ACYP4F2CYP4A11 | |
| SCHEMBL24338568 | 0.72 | SMN1; SMN2 (0.37) | HPGDEGFRKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL29491521 | 0.72 | SMN1; SMN2 (0.37) | HPGDTSHRMAPTKDM4EALDH1A1 | |
| SCHEMBL2961579 | 0.71 | PDE4B (0.36) | HPGDTSHRMAPTEGFRKDM4E | |
| SCHEMBL684345 | 0.69 | KDM4E (0.51) | HPGDTSHRMAPTEGFRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022068772-A1 | BENZIMIDAZOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 深圳信立泰药业股份有限公司 | 2022-04-07 | — | — | WO | disclosed |