SCHEMBL24339532

SCHEMBL24339532

CCCCCCCCOCCOP(=O)(O)OC[C@H]1O[C@@](C)(c2ccc3c(N)ncnn23)[C@H](O)[C@@H]1O

nearest known ligand 0.52

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ ADK P55263 6/20 0.38
▸ POLRMT O00411 1/20 0.37
▸ ENTPD1 P49961 2/20 0.35
▸ FGFR1 P11362 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25957154 1.00 ADK (0.38) ADKPOLRMTENTPD1FGFR1
SCHEMBL25957217 1.00 ADK (0.38) ADKPOLRMTENTPD1FGFR1
SCHEMBL25959790 1.00 ADK (0.38) ADKPOLRMTENTPD1FGFR1
SCHEMBL24407367 1.00 ADK (0.38) ADKPOLRMTENTPD1FGFR1
SCHEMBL24340445 1.00 ADK (0.38) ADKPOLRMTENTPD1FGFR1
SCHEMBL24407249 1.00 ADK (0.38) ADKPOLRMTENTPD1FGFR1
SCHEMBL24407366 1.00 ADK (0.38) ADKPOLRMTENTPD1FGFR1
SCHEMBL24407392 1.00 ADK (0.38) ADKPOLRMTENTPD1FGFR1
SCHEMBL25971388 0.98 ADK (0.40) ADKPOLRMTENTPD1FGFR1
SCHEMBL25971387 0.98 ADK (0.40) ADKPOLRMTENTPD1FGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230248753-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2023-08-10 — — US disclosed
US-20220143052-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2022-05-12 — — US disclosed
WO-2022081973-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. (US) 2022-04-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220143052-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF PHOSPHO1, SGMS2, SGMS1 ADK 1209/4885POLRMT 361/4885ENTPD1 440/4885
US-20230248753-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF PHOSPHO1, SGMS2, SGMS1 ADK 1209/4885POLRMT 361/4885ENTPD1 440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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