Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CASP2 | P42575 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18404646 | 0.83 | KMT2A (0.42) | KMT2AMEN1EPHX2CNR1RECQL | |
| SCHEMBL27383994 | 0.78 | ALDH1A1 (0.47) | KMT2AMEN1EPHX2CNR1FAAH | |
| SCHEMBL6358125 | 0.75 | KMT2A (0.59) | KMT2AMEN1RECQLLMNAMAPT | |
| SCHEMBL14176710 | 0.75 | MEN1 (0.48) | KMT2AMEN1EPHX2RECQL | |
| SCHEMBL14615690 | 0.74 | CASP2 (0.42) | EPHX2CNR1CASP2FAAH | |
| SCHEMBL21320744 | 0.74 | MEN1 (0.47) | KMT2AMEN1CNR1RECQLMTNR1A | |
| SCHEMBL15855131 | 0.74 | KMT2A (0.63) | KMT2AMEN1RECQLLMNAMAPT | |
| SCHEMBL13172394 | 0.73 | MEN1 (0.56) | KMT2AMEN1EPHX2RECQLMTNR1A | |
| SCHEMBL13033063 | 0.72 | KMT2A (0.61) | KMT2AMEN1EPHX2RECQLLMNA | |
| SCHEMBL1471554 | 0.72 | CA1 (0.42) | EPHX2RECQLLMNAACHEFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022056273-A1 | LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS | Arrowhead Pharmaceuticals, Inc. (US) | 2022-03-17 | — | — | WO | disclosed |