Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404829 | 0.93 | CYP1A2 (0.50) | CYP1A2SPHK2NFE2L2 | |
| SCHEMBL6937266 | 0.91 | CYP1A2 (0.54) | CYP1A2SPHK2NFE2L2 | |
| SCHEMBL3489813 | 0.88 | — | — | |
| SCHEMBL24042735 | 0.85 | NFE2L2 (0.39) | CYP1A2NFE2L2 | |
| SCHEMBL28329353 | 0.85 | NFE2L2 (0.38) | CYP1A2NFE2L2 | |
| SCHEMBL23014885 | 0.83 | CYP1A2 (0.50) | CYP1A2SPHK2MEN1THRBHTT | |
| SCHEMBL12461290 | 0.81 | — | — | |
| SCHEMBL21938959 | 0.80 | CYP1A2 (0.44) | CYP1A2NFE2L2MEN1HTTKMT2A | |
| SCHEMBL6437482 | 0.80 | CYP1A2 (0.64) | CYP1A2HRH3 | |
| SCHEMBL7765919 | 0.80 | CYP1A2 (0.64) | CYP1A2NFE2L2TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3981819-B1 | NOVEL REAGENTS FOR DIRECTED BIOMARKER SIGNAL AMPLIFICATION | SIRIGEN II LTD (GB) | 2024-02-28 | — | — | EP | disclosed |
| EP-3981819-A2 | NOVEL REAGENTS FOR DIRECTED BIOMARKER SIGNAL AMPLIFICATION | Sirigen II Limited (GB) | 2022-04-13 | — | — | EP | disclosed |