Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404829 | 0.98 | CYP1A2 (0.50) | CYP1A2NFE2L2SIGMAR1SMN1; SMN2SPHK2 | |
| SCHEMBL24340615 | 0.91 | CYP1A2 (0.43) | CYP1A2NFE2L2SPHK2 | |
| SCHEMBL7765919 | 0.89 | CYP1A2 (0.64) | CYP1A2NFE2L2SIGMAR1SMN1; SMN2 | |
| SCHEMBL6437482 | 0.89 | CYP1A2 (0.64) | CYP1A2SIGMAR1SMN1; SMN2NAAAEPHX1 | |
| SCHEMBL3489813 | 0.88 | — | — | |
| SCHEMBL11224710 | 0.88 | CYP1A2 (0.46) | CYP1A2NFE2L2SIGMAR1SMN1; SMN2EPHX1 | |
| SCHEMBL8743871 | 0.88 | CYP1A2 (0.46) | CYP1A2NFE2L2SIGMAR1SMN1; SMN2EPHX1 | |
| SCHEMBL21938959 | 0.85 | CYP1A2 (0.44) | CYP1A2NFE2L2SIGMAR1SMN1; SMN2EPHX1 | |
| SCHEMBL8986251 | 0.85 | NFE2L2 (0.42) | CYP1A2NFE2L2SIGMAR1SMN1; SMN2EPHX1 | |
| SCHEMBL10648552 | 0.85 | CYP1A2 (0.59) | CYP1A2SIGMAR1SPHK2NAAAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341512-A1 | RHINOLOGICAL AGENTS | HAARMANN & REIMER GMBH (DE) | 2003-09-10 | — | — | EP | claimed |
| WO-2002041861-A1 | RHINOLOGICAL AGENTS | HAARMANN & REIMER GMBH (DE) | 2002-05-30 | — | — | WO | claimed |