Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25854833 | 0.91 | SMN1; SMN2 (0.39) | SMN1; SMN2HPGDHTTCYP2C19TSHR | |
| SCHEMBL20926869 | 0.88 | HPGD (0.33) | SMN1; SMN2HPGDHTTCYP2C19TSHR | |
| SCHEMBL20926880 | 0.84 | HPGD (0.33) | SMN1; SMN2HPGDHTTCYP2C19TSHR | |
| SCHEMBL23948522 | 0.84 | HPGD (0.39) | SMN1; SMN2HPGDHTTCYP2C19KDM4E | |
| SCHEMBL20056990 | 0.83 | HPGD (0.34) | SMN1; SMN2HPGDHTTPOLB | |
| SCHEMBL10086140 | 0.82 | HPGD (0.33) | SMN1; SMN2HPGDHTTCYP2C19TSHR | |
| SCHEMBL21727787 | 0.82 | HPGD (0.33) | SMN1; SMN2HPGDHTTCYP2C19TSHR | |
| SCHEMBL26049697 | 0.81 | HPGD (0.30) | SMN1; SMN2HPGDHTTKDM4EALDH1A1 | |
| SCHEMBL27381401 | 0.79 | — | — | |
| SCHEMBL15146942 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2HPGDHTTCYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022056273-A1 | LIPID CONJUGATES FOR THE DELIVERY OF THERAPEUTIC AGENTS | Arrowhead Pharmaceuticals, Inc. (US) | 2022-03-17 | — | — | WO | disclosed |