Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10086140 | 0.89 | HPGD (0.33) | HPGDHTTSMN1; SMN2POLBHSD17B10 | |
| SCHEMBL24340751 | 0.88 | SMN1; SMN2 (0.41) | HPGDHTTSMN1; SMN2POLBCYP2C19 | |
| SCHEMBL20056990 | 0.87 | HPGD (0.34) | HPGDHTTSMN1; SMN2POLBHSD17B10 | |
| SCHEMBL21727787 | 0.86 | HPGD (0.33) | HPGDHTTSMN1; SMN2POLBHSD17B10 | |
| SCHEMBL20926880 | 0.86 | HPGD (0.33) | HPGDHTTSMN1; SMN2POLBHSD17B10 | |
| SCHEMBL20057063 | 0.80 | ALDH1A1 (0.35) | HPGDHTTSMN1; SMN2POLBHSD17B10 | |
| SCHEMBL13670141 | 0.79 | HTT (0.42) | HPGDHTTSMN1; SMN2POLBHSD17B10 | |
| SCHEMBL26049697 | 0.79 | HPGD (0.30) | HPGDHTTSMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL24826692 | 0.79 | POLB (0.33) | HPGDHTTSMN1; SMN2POLBHSD17B10 | |
| SCHEMBL24860019 | 0.79 | POLB (0.33) | HPGDHTTSMN1; SMN2POLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190120856-A1 | DETECTION OF SYMMETRICAL DIMETHYLARGININE | IDEXX LABORATORIES, INC. | 2019-04-25 | — | — | US | disclosed |