SCHEMBL2434232

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12291846	0.83	EGLN1 (0.58)	EGLN1MEN1MAPTKMT2AHDAC6
	SCHEMBL2437700	0.83	EGLN1 (0.45)	EGLN1MEN1MAPTKMT2AHIF1A
	SCHEMBL2581055	0.82	EGLN1 (0.56)	EGLN1HIF1A
	SCHEMBL2436448	0.81	EGLN1 (0.47)	EGLN1MEN1MAPTKMT2AHDAC6
	SCHEMBL2438657	0.79	ALDH1A1 (0.55)	MEN1KMT2AKDM4EALDH1A1LMNA
	SCHEMBL2439372	0.77	EGLN1 (0.49)	EGLN1MEN1KMT2AKDM4EALDH1A1
	SCHEMBL2437514	0.77	EGLN1 (0.54)	EGLN1MEN1MAPTKMT2AHDAC6
	SCHEMBL2441428	0.77	EGLN1 (0.69)	EGLN1HIF1A
	SCHEMBL2578864	0.76	L3MBTL1 (0.43)	EGLN1MEN1KMT2AKDM4EALDH1A1
	SCHEMBL2578859	0.76	L3MBTL1 (0.43)	EGLN1MEN1KMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.