Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 17/20 | 0.50 |
| ▸ | HEXA | P06865 | 1/20 | 0.36 |
| ▸ | HEXB | P07686 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2438488 | 0.79 | PIK3CD (0.56) | PIK3CD | |
| SCHEMBL2430725 | 0.79 | PIK3CD (0.44) | PIK3CD | |
| SCHEMBL1312945 | 0.75 | PIK3CD (0.64) | PIK3CDATMDRD4DRD3L3MBTL1 | |
| SCHEMBL4442988 | 0.74 | PIK3CD (0.63) | PIK3CDATMDRD4DRD3L3MBTL1 | |
| SCHEMBL1597713 | 0.74 | PIK3CD (0.65) | PIK3CDATMDRD4DRD3L3MBTL1 | |
| SCHEMBL1598041 | 0.73 | PIK3CD (0.64) | PIK3CDATMDRD4DRD3L3MBTL1 | |
| SCHEMBL1886097 | 0.73 | PIK3CD (0.64) | PIK3CDATMDRD4DRD3L3MBTL1 | |
| SCHEMBL1313281 | 0.73 | PIK3CD (0.56) | PIK3CDDRD4DRD3L3MBTL1 | |
| SCHEMBL1313191 | 0.72 | PIK3CD (0.58) | PIK3CD | |
| SCHEMBL6745119 | 0.69 | PIK3CD (0.62) | PIK3CDATMDRD4DRD3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2365810-A2 | PHOSPHATIDYLINOSITOL-3-KINASE P110 DELTA-TARGETED DRUGS IN THE TREATMENT OF CNS DISORDERS | The U.S.A. As Represented By The Secretary, Department Of Health And Human Services (US) | 2011-09-21 | — | — | EP | disclosed |
| WO-2010065923-A2 | PHOSPHATIDYLINOSITOL-3-KINASE P110 DELTA-TARGETED DRUGS IN THE TREATMENT OF CNS DISORDERS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2010-06-10 | — | — | WO | disclosed |