Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 16/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1312945 | 0.91 | PIK3CD (0.64) | PIK3CDATMDRD4DRD3L3MBTL1 | |
| SCHEMBL1597713 | 0.86 | PIK3CD (0.65) | PIK3CDATMDRD4DRD3L3MBTL1 | |
| SCHEMBL1886097 | 0.85 | PIK3CD (0.64) | PIK3CDATMDRD4DRD3L3MBTL1 | |
| SCHEMBL1598041 | 0.85 | PIK3CD (0.64) | PIK3CDATMDRD4DRD3L3MBTL1 | |
| SCHEMBL4433320 | 0.82 | PIK3CD (0.43) | PIK3CD | |
| SCHEMBL4441908 | 0.80 | PIK3CD (0.45) | PIK3CDL3MBTL1GAA | |
| SCHEMBL4178087 | 0.79 | DPP4 (0.51) | PIK3CD | |
| SCHEMBL4184546 | 0.79 | PIK3CD (0.55) | PIK3CDATMDRD4DRD3L3MBTL1 | |
| SCHEMBL2438488 | 0.78 | PIK3CD (0.56) | PIK3CD | |
| SCHEMBL789098 | 0.77 | PIK3CD (0.90) | PIK3CDATMDRD4DRD3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2137186-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USES | Amgen Inc. (US) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008118468-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USES | AMGEN INC. (US) | 2008-10-02 | — | — | WO | disclosed |