Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | JUN | P05412 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
| ▸ | TYK2 | P29597 | 2/20 | 0.33 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2435446 | 0.85 | ATR (0.49) | ATRP2RX3CA12CA1CA2 | |
| SCHEMBL24342423 | 0.84 | ATR (0.38) | ATRP2RX3CA12CA1CA2 | |
| SCHEMBL18746337 | 0.81 | ATR (0.39) | ATRP2RX3CA12CA1CA2 | |
| SCHEMBL2438709 | 0.81 | ATR (0.38) | ATRP2RX3CA12CA1CA2 | |
| SCHEMBL30726361 | 0.80 | ATR (0.43) | ATRP2RX3CA12CA1CA2 | |
| SCHEMBL18298896 | 0.80 | ATR (0.43) | ATRP2RX3CA12CA1CA2 | |
| SCHEMBL4001036 | 0.79 | ATR (0.39) | ATRP2RX3CA12CA1CA2 | |
| SCHEMBL20850921 | 0.79 | ATR (0.39) | ATRCA12CA1CA2CA9 | |
| SCHEMBL15712435 | 0.78 | ATR (0.38) | ATRCA12CA1CA2CA9 | |
| SCHEMBL15712602 | 0.78 | ATR (0.38) | ATRP2RX3CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081912-A2 | HETEROCYCLES AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2022-04-21 | — | — | WO | disclosed |