Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 7/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 7/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 6/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.36 |
| ▸ | GABRP | O00591 | 3/20 | 0.36 |
| ▸ | GABRD | O14764 | 3/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.36 |
| ▸ | GABRE | P78334 | 3/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.36 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2438709 | 0.94 | ATR (0.38) | ATRGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL2435446 | 0.86 | ATR (0.49) | ATRP2RX3CA12CA1CA2 | |
| SCHEMBL18298896 | 0.84 | ATR (0.43) | ATRGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL30726361 | 0.84 | ATR (0.43) | ATRGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL24342425 | 0.84 | ATR (0.39) | ATRP2RX3CA12CA1CA2 | |
| SCHEMBL17671029 | 0.83 | L3MBTL1 (0.40) | ATRGABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL4001036 | 0.83 | ATR (0.39) | ATRGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL20850921 | 0.83 | ATR (0.39) | ATRGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL15712602 | 0.81 | ATR (0.38) | ATRGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL15712435 | 0.81 | ATR (0.38) | ATRGABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022081912-A2 | HETEROCYCLES AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2022-04-21 | — | — | WO | disclosed |