Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH2 | P48735 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.40 |
| ▸ | RHOA | P61586 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.38 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | OGG1 | O15527 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23976663 | 0.80 | MEN1 (0.48) | ALDH1A1MEN1MAPTKMT2AMAPK1 | |
| SCHEMBL15102360 | 0.79 | ADORA1 (0.59) | IDH2ADORA1RHOAADORA2AKCNH3 | |
| SCHEMBL15102281 | 0.78 | IDH2 (0.55) | IDH2ADORA1RHOAADORA2AKCNH3 | |
| SCHEMBL15102600 | 0.76 | ADORA3 (0.59) | IDH2ADORA1RHOAADORA2AADORA3 | |
| SCHEMBL15094720 | 0.74 | IDH2 (0.59) | IDH2RHOAPDE4BPDE4DKCNH3 | |
| SCHEMBL15094936 | 0.74 | IDH2 (0.53) | IDH2RHOAPDE4BPDE4DALDH1A1 | |
| SCHEMBL15102519 | 0.73 | LMNA (0.54) | IDH2RHOAADORA3ALDH1A1MEN1 | |
| SCHEMBL15124116 | 0.72 | IDH2 (0.57) | IDH2ADORA1RHOAPDE4BPDE4D | |
| SCHEMBL15094812 | 0.72 | IDH2 (0.54) | IDH2ADORA1RHOAPDE4BPDE4D | |
| SCHEMBL15094752 | 0.71 | IDH2 (0.56) | IDH2RHOAKCNH3ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3984997-A1 | THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE | Les Laboratoires Servier SAS (FR) | 2022-04-20 | — | — | EP | disclosed |