SCHEMBL24343371

SCHEMBL24343371

c1ccc(-c2cccc(-c3nc(-c4ccccc4)nc(-c4ccc(-c5ccc6oc7ccccc7c6c5)c5ccccc45)n3)c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PLA2G2A P14555 4/20 0.44
▸ PLA2G4A P47712 4/20 0.44
▸ PLA2G10 O15496 1/20 0.44
▸ ALDH1A1 P00352 3/20 0.39
▸ HPGD P15428 3/20 0.39
▸ MAPT P10636 3/20 0.39
▸ KDM4E B2RXH2 2/20 0.39
▸ NPC1 O15118 2/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.39
▸ CHEK2 O96017 1/20 0.38
▸ GAA P10253 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ ALOX5 P09917 1/20 0.37
▸ PRKDC P78527 1/20 0.37
▸ CASP3 P42574 1/20 0.36
▸ SENP7 Q9BQF6 1/20 0.36
▸ SENP6 Q9GZR1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23385055 0.96 PLA2G2A (0.43) PLA2G2APLA2G4APLA2G10ALDH1A1HPGD
SCHEMBL15501841 0.95 PLA2G2A (0.45) PLA2G2APLA2G4APLA2G10ALDH1A1HPGD
SCHEMBL23385227 0.95 MAPT (0.42) PLA2G2APLA2G4APLA2G10ALDH1A1HPGD
SCHEMBL23027682 0.92 PLA2G2A (0.40) PLA2G2APLA2G4APLA2G10ALDH1A1HPGD
SCHEMBL24343372 0.92 PLA2G2A (0.41) PLA2G2APLA2G4APLA2G10ALDH1A1HPGD
SCHEMBL25664595 0.92 PLA2G2A (0.41) PLA2G2APLA2G4APLA2G10ALDH1A1HPGD
SCHEMBL15501614 0.92 PLA2G2A (0.45) PLA2G2APLA2G4APLA2G10ALDH1A1HPGD
SCHEMBL21109060 0.92 PLA2G2A (0.50) PLA2G2APLA2G4APLA2G10ALDH1A1HPGD
SCHEMBL21108989 0.92 PLA2G2A (0.50) PLA2G2APLA2G4APLA2G10ALDH1A1HPGD
SCHEMBL21109063 0.92 PLA2G2A (0.50) PLA2G2APLA2G4APLA2G10ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220384744-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-12-01 — — US disclosed
US-20220123233-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2022-04-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220123233-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME PIEZO1, LIMS1, MAL2 PLA2G2A 2828/4885PLA2G4A 2148/4885PLA2G10 2154/4885
US-20220384744-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TELO2, PIEZO1, LIMS1 PLA2G2A 2942/4885PLA2G4A 2232/4885PLA2G10 2027/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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