SCHEMBL2434416

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2435402	0.83	EGLN1 (0.39)	ALDH1A1KDM4ENPC1RAB9ALMNA
	SCHEMBL2587838	0.83	L3MBTL1 (0.39)	ALDH1A1KDM4ENPC1RAB9ALMNA
	SCHEMBL2587836	0.83	L3MBTL1 (0.39)	ALDH1A1KDM4ENPC1RAB9ALMNA
	SCHEMBL2577023	0.83	EGLN1 (0.44)	TSHREGLN1
	SCHEMBL2576901	0.80	EGLN1 (0.55)	EGLN1
	SCHEMBL2443706	0.79	EGLN1 (0.52)	ALDH1A1KDM4ENPC1RAB9ALMNA
	SCHEMBL2582874	0.79	L3MBTL1 (0.42)	ALDH1A1KDM4ENPC1RAB9ALMNA
	SCHEMBL2582480	0.79	L3MBTL1 (0.42)	ALDH1A1KDM4ENPC1RAB9ALMNA
	SCHEMBL336867	0.78	ALDH1A1 (0.41)	ALDH1A1KDM4ENPC1RAB9ALMNA
	SCHEMBL2576293	0.78	EGLN1 (0.42)	TSHREGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.