SCHEMBL24344713

SCHEMBL24344713

CSc1c(C)cc(C(C)(C)C)cc1C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.41
HTR1D P28221 5/20 0.36
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
ALDH1A1 P00352 4/20 0.34
TSHR P16473 4/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
ALOX15 P16050 3/20 0.34
CYP3A4 P08684 3/20 0.34
TP53 P04637 2/20 0.34
MAPK1 P28482 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
HIF1A Q16665 1/20 0.34
HTR1B P28222 3/20 0.33
CYP1A2 P05177 3/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
CA2 P00918 1/20 0.32
TYR P14679 1/20 0.32
HTR1A P08908 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14640959 0.89 GABRA1 (0.39) POLBHTR1DGABRA1GABRB2ALDH1A1
SCHEMBL24344714 0.83 SMN1; SMN2 (0.46) POLBALDH1A1TSHRSMN1; SMN2ALOX15
SCHEMBL21950842 0.78 HIF1A (0.34) GABRA1GABRB2ALDH1A1TSHRALOX15
SCHEMBL3178010 0.77 GABRA1 (0.40) POLBHTR1DGABRA1GABRB2ALDH1A1
SCHEMBL24344711 0.76 CYP1A2 (0.38) HTR1DALDH1A1TSHRSMN1; SMN2ALOX15
SCHEMBL11357994 0.76 POLB (0.46) POLBHTR1DGABRA1GABRB2ALDH1A1
SCHEMBL21950844 0.75 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL2631798 0.75 SMN1; SMN2 (0.52) POLBALDH1A1TSHRSMN1; SMN2ALOX15
SCHEMBL18802806 0.74 GABRA1 (0.39) POLBGABRA1GABRB2ALDH1A1TSHR
SCHEMBL896031 0.74 POLB (0.50) POLBHTR1DGABRA1GABRB2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220085302-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-03-17 US disclosed
CN-107955089-B Post-treatment process for solution polymerization 中国石化扬子石油化工有限公司 2020-09-11 CN disclosed
CN-105524217-A Bimodal molecular weight distributed cycloolefin copolymer and preparation method thereof UNIV ZHEJIANG 2016-04-27 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220085302-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, LBR, EPOR POLB 2638/4885HTR1D 3276/4885GABRA1 460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.