SCHEMBL3178010

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14640959	0.82	GABRA1 (0.39)	GABRA1GABRB2POLBALDH1A1ALOX15
	SCHEMBL3177948	0.78	GABRA1 (0.36)	GABRA1GABRB2POLBALDH1A1ALOX15
	SCHEMBL3176272	0.77	GABRA1 (0.34)	GABRA1GABRB2POLBALDH1A1ALOX15
	SCHEMBL24344713	0.77	POLB (0.41)	GABRA1GABRB2POLBALDH1A1ALOX15
	SCHEMBL9173094	0.77	ALDH1A1 (0.46)	GABRA1GABRB2POLBALDH1A1ALOX15
	SCHEMBL896031	0.76	POLB (0.50)	GABRA1GABRB2POLBALDH1A1ALOX15
	SCHEMBL3175072	0.75	GABRA1 (0.33)	GABRA1GABRB2POLBALDH1A1ALOX15
	SCHEMBL7136246	0.72	GABRA1 (0.43)	GABRA1GABRB2POLBALDH1A1ALOX15
	SCHEMBL11357994	0.72	POLB (0.46)	GABRA1GABRB2POLBALDH1A1ALOX15
	SCHEMBL13280565	0.72	GABRA1 (0.43)	GABRA1GABRB2POLBALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.