SCHEMBL2434490

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2427836	1.00	GFER (0.41)	GFERITGB1ITGA4PTGS2CRACR2A
	SCHEMBL2434510	0.87	RAB9A (0.41)	GFERTP53ALDH1A1KDM4EMAPT
	SCHEMBL2431289	0.87	RAB9A (0.41)	GFERTP53ALDH1A1KDM4EMAPT
	SCHEMBL2432524	0.87	KMT2A (0.41)	TP53KMT2AKDM4EMEN1
	SCHEMBL2432516	0.87	KMT2A (0.41)	TP53KMT2AKDM4EMEN1
	SCHEMBL2431809	0.86	CRACR2A (0.40)	CRACR2ATP53AGTR1
	SCHEMBL2430581	0.86	DGAT1 (0.33)	KMT2AMEN1
	SCHEMBL2430585	0.86	DGAT1 (0.33)	KMT2AMEN1
	SCHEMBL2431812	0.86	CRACR2A (0.40)	CRACR2ATP53AGTR1
	SCHEMBL2428556	0.86	HSD17B10 (0.41)	ALDH1A1KMT2AMAPTMEN1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.