Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.42 |
| ▸ | BMP1 | P13497 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15526439 | 0.86 | DPP4 (0.43) | PYCR1KDM4EDGAT1ACACBFPR2 | |
| SCHEMBL13003912 | 0.84 | PYCR1 (0.43) | PYCR1BMP1PDPK1KDM4EMAPT | |
| SCHEMBL3904974 | 0.82 | IDO1 (0.43) | KDM4ESLC6A4 | |
| SCHEMBL31173173 | 0.82 | PYCR1 (0.44) | PYCR1BMP1PDPK1KDM4EDGAT1 | |
| SCHEMBL2879127 | 0.82 | PYCR1 (0.44) | PYCR1BMP1PDPK1KDM4EDGAT1 | |
| SCHEMBL8252272 | 0.82 | PYCR1 (0.46) | PYCR1BMP1PDPK1KDM4EDGAT1 | |
| SCHEMBL5239737 | 0.80 | PYCR1 (0.45) | PYCR1BMP1PDPK1KDM4EMAPT | |
| SCHEMBL27578151 | 0.79 | KDM1A (0.41) | PYCR1PDPK1MAPTKDM1ASLC6A4 | |
| SCHEMBL14478258 | 0.79 | PYCR1 (0.44) | PYCR1 | |
| SCHEMBL4004992 | 0.77 | GABRA1 (0.44) | KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011109679-A2 | INHIBITORS OF 5-LIPOXYGENASE | AMIRA PHARMACEUTICALS, INC. (US) | 2011-09-09 | — | — | WO | disclosed |