SCHEMBL24344935

SCHEMBL24344935

COc1nc(C)c(F)c(OC)c1C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SQOR Q9Y6N5 1/20 0.31
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31276989 0.79
SCHEMBL24344481 0.79
SCHEMBL27988452 0.69 F10 (0.40) HSD17B10
SCHEMBL16387373 0.69 SQOR (0.35) SQOR
SCHEMBL15443926 0.68 DYRK1A (0.36)
SCHEMBL30505748 0.67 KMT2A (0.39) SQOR
SCHEMBL29131660 0.67 KMT2A (0.39) SQOR
SCHEMBL22148919 0.67
SCHEMBL14877470 0.66 IMPDH2 (0.33) HSD17B10
SCHEMBL24258181 0.66 IMPDH2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022076975-A1 5- AND 6-AZAINDOLE COMPOUNDS FOR INHIBITION OF BCR-ABL TYROSINE KINASES ENLIVEN THERAPEUTICS, INC. (US) 2022-04-14 WO disclosed