Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.67 |
| ▸ | MEN1 | O00255 | 8/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | PKM | P14618 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | XBP1 | P17861 | 1/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1753097 | 0.94 | MAPT (0.73) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9300939 | 0.85 | KMT2A (0.69) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL16080106 | 0.85 | MAPT (0.62) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL197261 | 0.80 | MAPT (0.75) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12267450 | 0.80 | MAPT (0.75) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL197262 | 0.80 | MAPT (0.75) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL19721178 | 0.80 | MAPT (0.68) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10577536 | 0.79 | MAPT (0.74) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10577532 | 0.79 | MAPT (0.74) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL20337574 | 0.76 | MAPT (0.57) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691135-B2 | Synthesis of alkynones via carbonylative Sonogashira coupling reactions catalyzed by Pd(II)-N-Heterocyclic carbene-pyridine complexes | KING FAHD UNIVERSITY OF PETROLEUM & MINERALS (SA) | 2023-07-04 | — | — | US | disclosed |
| US-20220118435-A1 | SYNTHESIS OF ALKYNONES VIA CARBONYLATIVE SONOGASHIRA COUPLING REACTIONS CATALYZED BY PD(II)-N-HETEROCYCLIC CARBENE-PYRIDINE COMPLEXES | KING FAHD UNIVERSITY OF PETROLEUM & MINERALS (SA) | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691135-B2 | Synthesis of alkynones via carbonylative Sonogashira coupling reactions catalyzed by Pd(II)-N-Heterocyclic carbene-pyridine complexes | PDK2, SNCA, YAP1 | MAPT 3784/4885KMT2A 1519/4885MEN1 1330/4885 |
| US-20220118435-A1 | SYNTHESIS OF ALKYNONES VIA CARBONYLATIVE SONOGASHIRA COUPLING REACTIONS CATALYZED BY PD(II)-N-HETEROCYCLIC CARBENE-PYRIDINE COMPLEXES | PDK2, SNCA, YAP1 | MAPT 3784/4885KMT2A 1519/4885MEN1 1330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.