SCHEMBL2434561

SCHEMBL2434561

O=C(O)c1ccc2c(c1C(=O)O)C(=O)OC2=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.53
MAPT P10636 7/20 0.40
ALDH1A1 P00352 6/20 0.40
CA12 O43570 5/20 0.40
CA7 P43166 5/20 0.40
CA1 P00915 4/20 0.40
KMT2A Q03164 4/20 0.40
MEN1 O00255 3/20 0.40
MAPK1 P28482 3/20 0.40
LMNA P02545 2/20 0.40
CA4 P22748 2/20 0.40
POLB P06746 1/20 0.40
THRB P10828 1/20 0.40
RECQL P46063 1/20 0.40
FTO Q9C0B1 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MMP14 P50281 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL759879 0.86 TYMS (0.51) TYMSMAPTALDH1A1CA12CA7
SCHEMBL11350894 0.86 TYMS (0.47) TYMSMAPTALDH1A1CA12CA7
SCHEMBL15104836 0.86 TYMS (0.44) TYMSMAPTALDH1A1CA12CA7
SCHEMBL2433833 0.85 TYMS (0.50) TYMSMAPTALDH1A1CA12CA7
SCHEMBL27658123 0.84 TYMS (0.51) TYMSMAPTALDH1A1CA12CA7
SCHEMBL18338732 0.82 ALDH1A1 (0.50) TYMSMAPTALDH1A1CA12CA7
SCHEMBL25187023 0.80 TYMS (0.51) TYMSMAPTALDH1A1CA12CA7
SCHEMBL8221235 0.80 DPP4 (0.46) TYMSMAPTALDH1A1CA12CA7
SCHEMBL26123957 0.80 TYMS (0.56) TYMSMAPTALDH1A1CA12CA7
SCHEMBL6541546 0.80 TYMS (0.51) TYMSMAPTALDH1A1CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117534833-A PI material for chip packaging and preparation method and application thereof 合肥芯视界集成电路设计有限公司 2024-02-09 CN claimed
US-10738162-B2 High-temperature resistant modified silicon-containing cyanate ester resin as well as preparation method and application thereof SUZHOU TAIHU ELECTRIC ADVANCED MAT CO LTD (CN) 2020-08-11 US claimed
CN-110600745-A Preparation method of novel polyimide composite negative current collector for lithium ions 东莞市烯热材料科技有限公司 2019-12-20 CN claimed
US-20180251604-A1 HIGH-TEMPERATURE RESISTANT MODIFIED SILICON-CONTAINING CYANATE ESTER RESIN AS WELL AS PREPARATION METHOD AND APPLICATION THEREOF SUZHOU TAIHU ELECTRIC ADVANCED MATERIAL CO, LTD. 2018-09-06 US claimed
CN-104812804-A Copolymers of polyaminopolyolefins and polyanhydrides CHEVRON ORONITE CO 2015-07-29 CN claimed
US-7700667-B2 Dental resin composition, method of manufacture, and method of use thereof PENTRON CLINICAL TECHNOLOGIES, LLC (US) 2010-04-20 US claimed
US-20050192374-A1 Dental resin composition, method of manufacture, and method of use thereof KERR CORPORATION 2005-09-01 US claimed
EP-1036827-B1 Process for the preparation of paints to be exposed to bad weather FRAUNHOFER GES FORSCHUNG (DE) 2005-06-29 EP claimed
US-6750280-B1 MIXTURE WITH: MOLECULAR SIEVE BEING PARTIALLY LOADED WITH AT LEAST ONE AMINE, A FILLER CAPABLE OF RELEASING WATER UPON HEATING AT A TEMPERATURE ABOVE THE PROCESSING TEMPERATURE OF THE MIXTURE ATOFINA (FR) 2004-06-15 US claimed
EP-0851896-B1 FOAMABLE POLYESTER COMPOSITIONS HAVING A LOW LEVEL OF UNREACTED BRANCHING AGENT EASTMAN CHEM CO (US) 2001-08-08 EP claimed
EP-0733087-B1 CROSS-LINKING AGENTS FOR POLYMERS WITH ACID ANHYDRIDE GROUPS ATOCHEM ELF SA (FR) 2001-03-14 EP claimed
US-5792816-A ANHYDROUS MOLECULAR SIEVE POWDER OF ALKALINE OR ALKALINE EARTH ALUMINOSILICATE LOADED WITH AMINE CAPABLE OF CROSSLINKING POLYMER HAVING ANHYDRIDE GROUPS ELF ATOCHEM S.A. (FR) 1998-08-11 US claimed
EP-0851896-A1 FOAMABLE POLYESTER COMPOSITIONS HAVING A LOW LEVEL OF UNREACTED BRANCHING AGENT EASTMAN CHEMICAL COMPANY (US) 1998-07-08 EP claimed
US-5756594-A CATALYTIC POLYMERIZATION OF ALDEHYDE CARBOXYLATE MONOMER TO FORM POLYACETAL AND CROSSLINKING WITH POLYVINYL ETHERS, DIESTERS, DIEPOXIDES, ANHYDRIDES, DINITRILES AND DIACYL COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 1998-05-26 US claimed
US-5696176-A MELT BLENDING WITH POLYOLEFIN EASTMAN CHEMICAL COMPANY (US) 1997-12-09 US claimed
US-5633341-A REACTING AN ACID ANHYDRIDE AND STERIC HINDERES AROMATIC AMINE CIBA GEIGY CORPORATION (US) 1997-05-27 US claimed
WO-1997011126-A1 FOAMABLE POLYESTER COMPOSITIONS HAVING A LOW LEVEL OF UNREACTED BRANCHING AGENT EASTMAN CHEMICAL COMPANY (US) 1997-03-27 WO claimed
US-4094831-A TERPOLYMER OF A DIENE, OLEFIN AND A VINYL OR ACRYLIC EPOXY COMPOUND THE GOODYEAR TIRE & RUBBER COMPANY (US) 1978-06-13 US claimed
US-11926759-B2 Window, method of manufacturing window, and display device including window SAMSUNG DISPLAY CO., LTD. (KR) 2024-03-12 US disclosed
US-4094831-A TERPOLYMER OF A DIENE, OLEFIN AND A VINYL OR ACRYLIC EPOXY COMPOUND THE GOODYEAR TIRE & RUBBER COMPANY (US) 1978-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050192374-A1 Dental resin composition, method of manufacture, and method of use thereof GRM6, MPHOSPH6, H1-0 TYMS 4687/4885MAPT 3961/4885ALDH1A1 2492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.