SCHEMBL2434576

SCHEMBL2434576

COCC=C(C)C(=O)OC1C2CC3CC(C2)CC1C3

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 11/20 0.38
EPHX1 P07099 1/20 0.36
FDFT1 P37268 1/20 0.32
FKBP1A P62942 1/20 0.32
EPHX2 P34913 1/20 0.31
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21385044 0.83 HSD11B1 (0.40) HSD11B1EPHX1FDFT1FKBP1AEPHX2
SCHEMBL20768339 0.79 HSD11B1 (0.44) HSD11B1EPHX1FKBP1AEPHX2CYP2C9
SCHEMBL28439794 0.78 FDFT1 (0.39) HSD11B1EPHX1FDFT1FKBP1A
SCHEMBL2300010 0.78 HSD11B1 (0.43) HSD11B1EPHX1FKBP1AEPHX2CYP2C9
SCHEMBL8395211 0.75 HSD11B1 (0.47) HSD11B1EPHX1FKBP1AEPHX2CYP2C9
SCHEMBL14973424 0.73 HSD11B1 (0.40) HSD11B1EPHX1FKBP1AEPHX2CYP2C9
SCHEMBL2967397 0.72 FDFT1 (0.38) HSD11B1EPHX1FDFT1
SCHEMBL2967393 0.72 FDFT1 (0.38) HSD11B1EPHX1FDFT1
SCHEMBL6329865 0.72 HSD11B1 (0.39) HSD11B1EPHX1FKBP1AEPHX2CYP2C9
SCHEMBL418793 0.72 HSD11B1 (0.44) HSD11B1EPHX1FKBP1AEPHX2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2102156-B1 PHOTOACTIVE COMPOUNDS MERCK PATENT GMBH (DE) 2019-06-26 EP disclosed
EP-2078028-B1 PHOTOACTIVE COMPOUNDS AZ ELECTRONIC MATERIALS USA (US) 2011-09-07 EP disclosed
EP-2102184-A2 PHOTOACTIVE COMPOUNDS AZ Electronic Materials USA Corp. (US) 2009-09-23 EP disclosed
EP-2102156-A2 PHOTOACTIVE COMPOUNDS AZ Electronic Materials USA Corp. (US) 2009-09-23 EP disclosed
EP-2078028-A1 PHOTOACTIVE COMPOUNDS AZ Electronic Materials USA Corp. (US) 2009-07-15 EP disclosed
US-7547501-B2 Photoactive compounds AZ ELECTRONIC MATERIALS USA CORP. (US) 2009-06-16 US disclosed
WO-2008068617-A2 PHOTOACTIVE COMPOUNDS AZ ELECTRONIC MATERIALS USA CORP. (DE) 2008-06-12 WO disclosed
WO-2008068610-A2 PHOTOACTIVE COMPOUNDS AZ ELECTRONIC MATERIALS USA CORP. (DE) 2008-06-12 WO disclosed
WO-2008041123-A1 PHOTOACTIVE COMPOUNDS AZ ELECTRONIC MATERIALS USA CORP. (DE) 2008-04-10 WO disclosed
US-20080085463-A1 PHOTOACTIVE COMPOUNDS AZ ELECTRONICS MATERIALS USA CORP. 2008-04-10 US disclosed