SCHEMBL24348352

SCHEMBL24348352

CC(=N)/C=C(\O)c1cnc(NC(C)(C)C)nc1C(C)C

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPK3 P27361 1/20 0.31
MAPK8 P45983 2/20 0.31
MAPK9 P45984 2/20 0.31
ADORA3 P0DMS8 1/20 0.31
MAPK10 P53779 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24349480 0.78 CDK4 (0.43) MAPK8MAPK9MAPK10
SCHEMBL24349479 0.77 MAPK1 (0.43) MAPK3MAPK8MAPK9MAPK10
SCHEMBL24349004 0.76 HDAC3 (0.40)
SCHEMBL24348342 0.75 IGF1R (0.44)
SCHEMBL24349469 0.73 TDP1 (0.37)
SCHEMBL24349486 0.72 ACACB (0.31)
SCHEMBL24348344 0.71 LMNA (0.47)
SCHEMBL24348356 0.68 PTPN11 (0.43)
SCHEMBL14659066 0.59 MAPK8 (0.59) MAPK3MAPK8MAPK9ADORA3MAPK10
SCHEMBL23196386 0.59 MAPK8 (0.39) MAPK3MAPK8MAPK9ADORA3MAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022053803-A1 HERBICIDAL PYRIMIDINE DERIVATIVES MOA Technology Limited (GB) 2022-03-17 WO disclosed