Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK4 | O00444 | 2/20 | 0.39 |
| ▸ | PAK4 | O96013 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SGK1 | O00141 | 2/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24348566 | 0.79 | HTR2C (0.37) | PLK4PAK4SMN1; SMN2HTR2AHTR2C | |
| SCHEMBL30406140 | 0.79 | HTR2C (0.37) | PLK4PAK4SMN1; SMN2HTR2AHTR2C | |
| SCHEMBL26724325 | 0.76 | PLK4 (0.38) | PLK4PAK4SMN1; SMN2HTR2AHTR2C | |
| SCHEMBL61883 | 0.72 | PLK4 (0.53) | PLK4PAK4SMN1; SMN2HTR2AHTR2C | |
| SCHEMBL166657 | 0.68 | PLK4 (0.42) | PLK4PAK4SMN1; SMN2HTR2AHTR2C | |
| SCHEMBL12398424 | 0.68 | PLK4 (0.36) | PLK4PAK4SMN1; SMN2HTR2AHTR2C | |
| SCHEMBL2675945 | 0.68 | PDPK1 (0.43) | SMN1; SMN2ALDH1A1PDPK1CHEK1AURKA | |
| SCHEMBL24348563 | 0.68 | ALDH1A1 (0.39) | PLK4PAK4SMN1; SMN2HTR2CALDH1A1 | |
| SCHEMBL29478852 | 0.68 | PDPK1 (0.43) | SMN1; SMN2ALDH1A1PDPK1CHEK1AURKA | |
| SCHEMBL24802934 | 0.68 | CCNT1 (0.42) | SMN1; SMN2ALDH1A1PDPK1CHEK1AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022058920-A1 | CASEIN KINASE 1 DELTA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2022-03-24 | — | — | WO | disclosed |