Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.37 |
| ▸ | HTR2A | P28223 | 4/20 | 0.36 |
| ▸ | PLK4 | O00444 | 3/20 | 0.33 |
| ▸ | PAK4 | O96013 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | SGK1 | O00141 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24348566 | 1.00 | HTR2C (0.37) | HTR2CHTR2APLK4PAK4SMN1; SMN2 | |
| SCHEMBL24348512 | 0.81 | HTR2C (0.39) | HTR2CHTR2APLK4PAK4SMN1; SMN2 | |
| SCHEMBL24348564 | 0.79 | PLK4 (0.39) | HTR2CHTR2APLK4PAK4SMN1; SMN2 | |
| SCHEMBL24349703 | 0.79 | ACHE (0.44) | HTR2CHTR2APLK4PAK4SMN1; SMN2 | |
| SCHEMBL26719826 | 0.76 | HTR2C (0.35) | HTR2CHTR2APLK4PAK4SMN1; SMN2 | |
| SCHEMBL29478852 | 0.68 | PDPK1 (0.43) | SMN1; SMN2ALDH1A1PDPK1CHEK1AURKA | |
| SCHEMBL2675945 | 0.68 | PDPK1 (0.43) | SMN1; SMN2ALDH1A1PDPK1CHEK1AURKA | |
| SCHEMBL24348563 | 0.68 | ALDH1A1 (0.39) | HTR2CPLK4PAK4SMN1; SMN2ALDH1A1 | |
| SCHEMBL23858513 | 0.68 | CCNT1 (0.42) | SMN1; SMN2ALDH1A1PDPK1HTTCHEK1 | |
| SCHEMBL2638970 | 0.67 | FGFR1 (0.35) | HTR2CHTR2APLK4PAK4SGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116171280-A | Casein kinase 1 delta modulators | 詹森药业有限公司 | 2023-05-26 | — | — | CN | disclosed |