Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 3/20 | 1.00 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 1.00 |
| ▸ | NPC1 | O15118 | 6/20 | 0.81 |
| ▸ | RAB9A | P51151 | 6/20 | 0.81 |
| ▸ | HPGD | P15428 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24348581 | 0.87 | ANO1 (0.77) | ANO1ANO2NPC1RAB9AHPGD | |
| SCHEMBL24349080 | 0.86 | ANO1 (1.00) | ANO1ANO2NPC1RAB9AHPGD | |
| SCHEMBL24349076 | 0.84 | NPC1 (0.76) | ANO1ANO2NPC1RAB9AHPGD | |
| SCHEMBL24349093 | 0.81 | NPC1 (0.71) | ANO1ANO2NPC1RAB9AHPGD | |
| SCHEMBL24348525 | 0.80 | ANO1 (0.67) | ANO1ANO2NPC1RAB9AHPGD | |
| SCHEMBL24349073 | 0.78 | ANO1 (1.00) | ANO1ANO2NPC1RAB9AHPGD | |
| SCHEMBL24349545 | 0.76 | ANO1 (0.68) | ANO1ANO2NPC1RAB9AHPGD | |
| SCHEMBL28570546 | 0.75 | NPC1 (0.64) | ANO1ANO2NPC1RAB9AHPGD | |
| SCHEMBL19002358 | 0.74 | ANO1 (0.59) | ANO1ANO2NPC1RAB9AHPGD | |
| SCHEMBL11389222 | 0.73 | NPC1 (0.61) | ANO1ANO2NPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11274074-B2 | Pharmaceutical composition for ANO1 antagonist with anticancer activity | INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY (KR) | 2022-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11274074-B2 | Pharmaceutical composition for ANO1 antagonist with anticancer activity | ANO1, ANO2, TMEM109 | ANO1 1/4885ANO2 2/4885NPC1 191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.