Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4576126 | 0.95 | PPARA (0.47) | PPARAPPARGL3MBTL1TDP1RAB9A | |
| SCHEMBL2439072 | 0.88 | PPARG (0.62) | PPARAPPARGL3MBTL1TDP1RAB9A | |
| SCHEMBL6781034 | 0.82 | PPARG (0.59) | PPARAPPARGL3MBTL1TDP1RAB9A | |
| SCHEMBL2440291 | 0.81 | PPARA (0.59) | PPARAPPARGNR1H2 | |
| SCHEMBL2438002 | 0.79 | PPARA (0.58) | PPARAPPARG | |
| SCHEMBL8801774 | 0.78 | NR1H2 (0.62) | L3MBTL1TDP1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL6543060 | 0.77 | PPARA (0.54) | PPARAPPARG | |
| SCHEMBL4840291 | 0.77 | RAB9A (0.50) | L3MBTL1TDP1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL30941023 | 0.76 | MAOB (0.43) | L3MBTL1TDP1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL4842190 | 0.76 | RAB9A (0.52) | L3MBTL1TDP1RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-B1 | Benzoxazole compound and pharmaceutical composition containing the compound | KOWA CO (JP) | 2011-09-21 | — | — | EP | disclosed |
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |