Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.62 |
| ▸ | PPARA | Q07869 | 8/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 3/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6781034 | 0.94 | PPARG (0.59) | PPARGPPARATDP1L3MBTL1MAPT | |
| SCHEMBL2434908 | 0.88 | PPARA (0.50) | PPARGPPARATDP1L3MBTL1MAPT | |
| SCHEMBL4576126 | 0.82 | PPARA (0.47) | PPARGPPARATDP1L3MBTL1MAPT | |
| SCHEMBL8801774 | 0.80 | NR1H2 (0.62) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL2434760 | 0.79 | PPARG (0.76) | PPARGPPARAPPARDCYP4F2CYP4A11 | |
| SCHEMBL2202629 | 0.78 | RAB9A (0.65) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL2206329 | 0.78 | GRM5 (0.61) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL2439451 | 0.78 | PPARA (0.74) | PPARGPPARAPPARDCYP4F2CYP4A11 | |
| SCHEMBL4569072 | 0.77 | RAB9A (0.53) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL2204230 | 0.77 | RAB9A (0.63) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-B1 | Benzoxazole compound and pharmaceutical composition containing the compound | KOWA CO (JP) | 2011-09-21 | — | — | EP | disclosed |
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-6653334-B1 | Electively activate peroxisome proliferator activated receptors | KOWA CO., LTD. (JP) | 2003-11-25 | — | — | US | disclosed |