Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGT1 | P19440 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 7/20 | 0.34 |
| ▸ | CPB1 | P15086 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3749598 | 0.81 | GGT1 (0.42) | GGT1GABRR1CPB2CPB1 | |
| SCHEMBL9450993 | 0.79 | GGT1 (0.36) | GGT1GABRR1CPB2CPB1 | |
| SCHEMBL17663617 | 0.75 | POLB (0.32) | — | |
| SCHEMBL28686249 | 0.73 | GGT1 (0.42) | GGT1GABRR1CPB2CPB1 | |
| SCHEMBL2436979 | 0.70 | GAA (0.39) | — | |
| SCHEMBL8038154 | 0.67 | GGT1 (0.37) | GGT1GABRR1 | |
| SCHEMBL19228114 | 0.66 | PTGS1 (0.50) | — | |
| SCHEMBL164972 | 0.66 | — | — | |
| SCHEMBL601790 | 0.66 | — | — | |
| SCHEMBL15453401 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697344-B1 | HIV PROTEASE INHIBITING COMPOUNDS | ABBOTT LAB (US) | 2011-09-28 | — | — | EP | disclosed |
| US-20100249181-A1 | HIV Protease Inhibiting Compounds | ABBOTT LABORATORIES (US) | 2010-09-30 | — | — | US | disclosed |
| US-20050131017-A1 | HIV protease inhibiting compounds | ABBOTT LABORATORIES | 2005-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050131017-A1 | HIV protease inhibiting compounds | SERPINB1, HPN, DNPEP | GGT1 205/4885GABRR1 2254/4885CPB2 113/4885 |
| US-20100249181-A1 | HIV Protease Inhibiting Compounds | SERPINB1, HPN, DNPEP | GGT1 205/4885GABRR1 2254/4885CPB2 113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.