Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 18/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29003185 | 1.00 | GPR119 (0.49) | GPR119NR1H2NR1H3 | |
| SCHEMBL29412831 | 1.00 | GPR119 (0.49) | GPR119NR1H2NR1H3 | |
| SCHEMBL29003150 | 0.87 | GPR119 (0.60) | GPR119 | |
| SCHEMBL29412824 | 0.87 | GPR119 (0.60) | GPR119 | |
| SCHEMBL24348654 | 0.87 | GPR119 (0.60) | GPR119 | |
| SCHEMBL29003136 | 0.84 | GPR119 (0.41) | GPR119 | |
| SCHEMBL29003138 | 0.84 | GPR119 (0.41) | GPR119 | |
| SCHEMBL30456370 | 0.84 | GPR119 (0.41) | GPR119 | |
| SCHEMBL29003123 | 0.77 | GPR119 (0.60) | GPR119 | |
| SCHEMBL38665357 | 0.74 | GPR119 (0.40) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157122-A | Imidazo [1,2-a ] pyridine compounds and their use in therapy | 帝国理工学院创新有限公司 | 2023-05-23 | — | — | CN | disclosed |
| WO-2022058745-A9 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AND THEIR USE IN THERAPY | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2022-05-27 | — | — | WO | disclosed |
| WO-2022058745-A2 | NOVEL COMPOUNDS AND THEIR USE IN THERAPY | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2022-03-24 | — | — | WO | disclosed |