SCHEMBL29003138

SCHEMBL29003138

CCC1CN(C(=O)OC(C)(C)C)CCN1c1ncc(Cl)c(SC)n1

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 15/20 0.41
POLB P06746 1/20 0.36
PARP1 P09874 1/20 0.36
PIK3CD O00329 1/20 0.36
CKS1B P61024 1/20 0.36
SKP1 P63208 1/20 0.36
SKP2 Q13309 1/20 0.36
ALK Q9UM73 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30456370 1.00 GPR119 (0.41) GPR119POLBPARP1PIK3CDCKS1B
SCHEMBL29003136 1.00 GPR119 (0.41) GPR119POLBPARP1PIK3CDCKS1B
SCHEMBL29412832 0.87 GPR119 (0.52) GPR119
SCHEMBL24348655 0.87 GPR119 (0.52) GPR119
SCHEMBL24348651 0.87 GPR119 (0.52) GPR119
SCHEMBL29003135 0.86 JAK3 (0.33)
SCHEMBL29003137 0.86 JAK3 (0.33)
SCHEMBL24349653 0.84 GPR119 (0.49) GPR119
SCHEMBL29412831 0.84 GPR119 (0.49) GPR119
SCHEMBL29003185 0.84 GPR119 (0.49) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116157122-A Imidazo [1,2-a ] pyridine compounds and their use in therapy 帝国理工学院创新有限公司 2023-05-23 CN disclosed