SCHEMBL2435286

SCHEMBL2435286

CC(=O)N(C(C)=O)c1nc2nc[nH]c2c(=O)[nH]1

nearest known ligand 0.57

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GDA Q9Y2T3 1/20 0.57
PNP P00491 1/20 0.51
ALDH1A1 P00352 1/20 0.46
GRIA1 P42261 1/20 0.44
GRIA2 P42262 1/20 0.44
GRIA3 P42263 1/20 0.44
GRIA4 P48058 1/20 0.44
XDH P47989 6/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8591405 0.84 GDA (0.52) GDAPNPALDH1A1GRIA1GRIA2
SCHEMBL595204 0.81 PNP (0.57) GDAPNPALDH1A1GRIA1GRIA2
Hydrochloric Acid SCHEMBL17186358 0.80 PNP (0.56) GDAPNPALDH1A1GRIA1GRIA2
Hydrochloric Acid SCHEMBL17186227 0.80 PNP (0.56) GDAPNPALDH1A1GRIA1GRIA2
SCHEMBL10629409 0.78 PNP (0.62) GDAPNPALDH1A1GRIA1GRIA2
SCHEMBL5323947 0.75 PNP (0.48) GDAPNPALDH1A1GRIA1GRIA2
SCHEMBL15194736 0.74 PNP (0.53) GDAPNPALDH1A1GRIA1GRIA2
Guanine SCHEMBL14125687 0.74 PNP (0.81) GDAPNPALDH1A1GRIA1GRIA2
SCHEMBL219478 0.73 GDA (1.00) GDAPNPXDH
SCHEMBL9275484 0.72 PNP (0.48) GDAPNPALDH1A1GRIA1GRIA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 258 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-222578802-U Diacetyl guanine production high-efficient drying device 洛阳德胜生物科技股份有限公司 2025-03-07 CN claimed
CN-115724845-B Triacetyl ganciclovir preparation method of pyrrosir 湖北省宏源药业科技股份有限公司 2025-02-11 CN claimed
CN-114047262-B Method for separating and measuring easily-hydrolyzed large polar compound 湖北省宏源药业科技股份有限公司 2024-12-13 CN claimed
CN-221999833-U Accurate temperature control device during diacetyl guanine reaction 洛阳德胜生物科技股份有限公司 2024-11-15 CN claimed
CN-113929580-B Method for recovering side chains in ganciclovir condensate mother liquor 湖北省宏源药业科技股份有限公司 2024-10-18 CN claimed
CN-114478531-B Method for recycling ganciclovir condensate synthetic mother liquor 湖北省宏源药业科技股份有限公司 2024-09-10 CN claimed
CN-118561846-A Acyclovir preparation method of pyrrosia lingua 拓新药业集团股份有限公司 2024-08-30 CN claimed
CN-221445833-U Diacetyl guanine concentration detector 通辽德胜生物科技有限公司 2024-07-30 CN claimed
CN-221131020-U Rectifying column for diacetylguanine production 新乡瑞诚科技股份有限公司 2024-06-14 CN claimed
CN-115367745-B Tungsten-containing substance hybridization and nitrogen-doped porous carbon material and preparation method thereof 北京化工大学 2023-11-24 CN claimed
EP-1453833-A2 A PROCESS FOR THE PREPARATION OF GANCICLOVIR INTERMEDIATE N2-ACETYL-9-(1,3-DIACETOXY-2-PROPOXYMETHYL) GUANINE RANBAXY LABORATORIES, LTD. (IN) 2004-09-08 EP claimed
WO-2004048380-A1 PROCESS FOR THE SYNTHESIS OF GANCICLOVIR RANBAXY LABORATORIES LIMITED (IN) 2004-06-10 WO claimed
US-20040102628-A1 Process for the synthesis of ganciclovir RANBAXY LABORATORIES LIMITED (IN) 2004-05-27 US claimed
WO-2004039808-A2 PROCESS FOR THE PREPARATION OF GANCICLOVIR RANBAXY LABORATORIES LIMITED (US) 2004-05-13 WO claimed
WO-2003033498-A2 A PROCESS FOR THE TREATMENT OF GANCICLOVIR INTERMEDIATE N2-ACETYL-9-(1, 3-DIACETOXY-2-PROPOXYMETHYL) GUANINE RANBAXY LABORATORIES LIMITED (IN) 2003-04-24 WO claimed
EP-0806425-B1 An improved regiospecific process for synthesis of acyclic nucleosides LUPIN LAB LTD (IN) 2001-08-29 EP claimed
US-5821367-A REACTING A DIACYLGUANINE AND AN ALKYLATING AGENT IN THE ABSENCE OF AN ACID CATALYST AND A SOLVENT LUPIN LABORATORIES LIMITED (IN) 1998-10-13 US claimed
EP-0806425-A1 An improved regiospecific process for synthesis of acyclic nucleosides LUPIN LABORATORIES LIMITED (IN) 1997-11-12 EP claimed
WO-1997024357-A1 PROCESS FOR SYNTHESIS AND PURIFICATION OF A COMPOUND USEFUL IN THE PREPARATION OF ACYCLOVIR MALLINCKRODT CHEMICAL, INC. (US) 1997-07-10 WO claimed
US-5583225-A REACTING N2, N9-DIPROTECTED GUANINE WITH DIACETOXYPROPANE IN THE PRESENCE OF A MIXTURE OF AN ACID AND ACETIC ANHYDRIDE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1996-12-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040102628-A1 Process for the synthesis of ganciclovir TYMP, MTAP, TPMT GDA 9/4885PNP 10/4885ALDH1A1 2906/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.