SCHEMBL595204

SCHEMBL595204

CN(C)c1nc2nc[nH]c2c(=O)[nH]1

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PNP P00491 1/20 0.57
ALDH1A1 P00352 1/20 0.52
GDA Q9Y2T3 1/20 0.51
GRIA1 P42261 1/20 0.49
GRIA2 P42262 1/20 0.49
GRIA3 P42263 1/20 0.49
GRIA4 P48058 1/20 0.49
XDH P47989 6/20 0.48
NUDT1 P36639 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL17186358 0.98 PNP (0.56) PNPALDH1A1GDAGRIA1GRIA2
Hydrochloric Acid SCHEMBL17186227 0.98 PNP (0.56) PNPALDH1A1GDAGRIA1GRIA2
SCHEMBL8591405 0.83 GDA (0.52) PNPALDH1A1GDAGRIA1GRIA2
SCHEMBL10629409 0.83 PNP (0.62) PNPALDH1A1GDAGRIA1GRIA2
SCHEMBL27501471 0.82 PNP (0.49) PNPALDH1A1GDAGRIA1GRIA2
SCHEMBL2435286 0.81 GDA (0.57) PNPALDH1A1GDAGRIA1GRIA2
SCHEMBL9275484 0.81 PNP (0.48) PNPALDH1A1GDAGRIA1GRIA2
SCHEMBL1898182 0.80 PNP (0.62) PNPALDH1A1GDAGRIA1GRIA2
SCHEMBL27504062 0.80 PNP (0.54) PNPALDH1A1GDAGRIA1GRIA2
SCHEMBL9059986 0.79 XDH (0.55) PNPALDH1A1GDAGRIA1GRIA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 796 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12584924-B2 Compositions and methods for diagnosing and treating chronic kidney disease SOCIETE DES PRODUITS NESTLE S.A. (CH) 2026-03-24 US claimed
EP-4457513-A1 COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING CHRONIC KIDNEY DISEASE Société des Produits Nestlé S.A. (CH) 2024-11-06 EP claimed
WO-2023126758-A1 COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING CHRONIC KIDNEY DISEASE Société des Produits Nestlé S.A. (CH) 2023-07-06 WO claimed
US-20230204604-A1 COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING CHRONIC KIDNEY DISEASE SOCIETE DES PRODUITS NESTLE S.A. (CH) 2023-06-29 US claimed
US-20220282275-A1 G-TO-T BASE EDITORS AND USES THEREOF THE BROAD INSTITUTE, INC. (US) 2022-09-08 US claimed
WO-2020102659-A1 G-TO-T BASE EDITORS AND USES THEREOF THE BROAD INSTITUTE, INC. (US) 2020-05-22 WO claimed
US-9828633-B1 Modified nucleotides methods and kits PIERCE BIOTECHNOLOGY, INC. (US) 2017-11-28 US claimed
EP-3074042-A1 COMPOSITIONS Globalacorn Ltd. (GB) 2016-10-05 EP claimed
US-9206216-B2 Modified nucleotides methods and kits PIERCE BIOTECHNOLOGY, INC. (US) 2015-12-08 US claimed
WO-2015079241-A1 COMPOSITIONS GLOBALACORN LTD (GB) 2015-06-04 WO claimed
US-20150119352-A1 DINUCELOSIDE POLYPHOSPHATES FOR THE TREATMENT OF PAIN GlobalAcornLtd. (GB) 2015-04-30 US claimed
EP-2669291-A1 Modified Nucleotides Methods and Kits Pierce Biotechnology, Inc. (US) 2013-12-04 EP claimed
US-8536323-B2 Modified nucleotides PIERCE BIOTECHNOLOGY, INC. (US) 2013-09-17 US claimed
US-20120252691-A1 MODIFIED NUCLEOTIDES METHODS AND KITS PIERCE BIOTECHNOLOGY, INC. (US) 2012-10-04 US claimed
US-20110262917-A1 MODIFIED NUCLEOTIDES PIERCE BIOTECHNOLOGY, INC. (US) 2011-10-27 US claimed
WO-2008033432-A2 IMMUNE MODULATION BY CHEMICALLY MODIFIED RIBONUCLEOSIDES AND OLIGORIBONUCLEOTIDES COLEY PHARMACEUTICAL GROUP, INC. (US) 2008-03-20 WO claimed
CN-1973821-A Medicine composition containing both anticancer medicine and its synergist SHANDONG LANJIN BIOENGINEERING (CN) 2007-06-06 CN claimed
EP-1525224-A1 HYALURONIC ACID DERIVATIVES Jasper Ltd. Liability Co. (US) 2005-04-27 EP claimed
WO-2004013182-A1 HYALURONIC ACID DERIVATIVES JASPER LTD LIABILITY CO. (US) 2004-02-12 WO claimed
US-20040009602-A1 DNA modifying molecules and methods of use thereof THE GOVERNMENT OF THE U.S.A. AS REPRESENTED BY THE SECRETARY OF THE DEPT. OF HEALTH & HUMAN SERVICES 2004-01-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150119352-A1 DINUCELOSIDE POLYPHOSPHATES FOR THE TREATMENT OF PAIN P2RX3, P2RX2, P2RY10 PNP 330/4885ALDH1A1 4482/4885GDA 1781/4885
US-20120252691-A1 MODIFIED NUCLEOTIDES METHODS AND KITS RNGTT, NUDT1, ADAR PNP 15/4885ALDH1A1 2292/4885GDA 79/4885
US-20110262917-A1 MODIFIED NUCLEOTIDES NUDT1, RNMT, RNGTT PNP 21/4885ALDH1A1 2422/4885GDA 109/4885
US-12584924-B2 Compositions and methods for diagnosing and treating chronic kidney disease GLS, AADAT, FGF23 PNP 241/4885ALDH1A1 822/4885GDA 1197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.