Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 7/20 | 0.33 |
| ▸ | CNR1 | P21554 | 6/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15506135 | 0.77 | ALDH1A1 (0.50) | ALDH1A1CYP1A1CYP1B1CA1CA2 | |
| SCHEMBL845798 | 0.77 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2CYP1A1CYP1B1CA1 | |
| SCHEMBL17129735 | 0.73 | ALDH1A1 (0.46) | ALDH1A1CYP1A1CYP1B1CA1CA2 | |
| SCHEMBL26032718 | 0.72 | ALDH1A1 (0.50) | ALDH1A1CYP1A1CYP1B1CA1CA2 | |
| SCHEMBL25965182 | 0.72 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2HSD17B10CYP1A1CYP1B1 | |
| SCHEMBL278798 | 0.71 | ALDH1A1 (0.61) | ALDH1A1HSD17B10CYP1A1CYP1B1CA1 | |
| SCHEMBL23162447 | 0.71 | ALDH1A1 (0.42) | ALDH1A1CYP1A1CYP1B1CA1CA2 | |
| SCHEMBL23802246 | 0.71 | CNR2 (0.50) | ALDH1A1CNR2CNR1TRPV1 | |
| SCHEMBL23162732 | 0.69 | RXRA (0.42) | ALDH1A1CNR2CNR1KDM4EGAA | |
| SCHEMBL18944636 | 0.69 | ALDH1A1 (0.41) | ALDH1A1CYP1A1CYP1B1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11311609-B2 | Regulating chimeric antigen receptors | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11311609-B2 | Regulating chimeric antigen receptors | NFATC1, TNFRSF9, IL2RA | ALDH1A1 4691/4885HPGD 4508/4885SMN1; SMN2 2808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.