Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | HPGD | P15428 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22248340 | 0.97 | KMT2A (0.35) | KMT2AMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL24355776 | 0.94 | MEN1 (0.34) | KMT2AMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL22248113 | 0.92 | KDM4E (0.35) | KMT2AMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL24355650 | 0.91 | PTGER4 (0.34) | KMT2AMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL24355645 | 0.91 | PTGER4 (0.34) | KMT2AMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL24355734 | 0.89 | PTGER4 (0.33) | KMT2AALDH1A1HPGDMEN1KDM4E | |
| SCHEMBL24355858 | 0.89 | PTGER4 (0.33) | KMT2AALDH1A1HPGDMEN1KDM4E | |
| SCHEMBL24355675 | 0.89 | KDM4E (0.39) | KMT2AMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL24355940 | 0.88 | PTGER4 (0.32) | KMT2AALDH1A1HPGDMEN1KDM4E | |
| SCHEMBL22248240 | 0.87 | KDM4E (0.36) | KMT2AMAPTALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127285-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127285-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | PIEZO1, LEF1, L1CAM | KMT2A 3222/4885MAPT 2573/4885ALDH1A1 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.