Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 7/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MPL | P40238 | 5/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24358021 | 0.81 | MEN1 (0.52) | LTA4HRAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL29601739 | 0.81 | MEN1 (0.52) | LTA4HRAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL18113734 | 0.77 | MPL (0.55) | LTA4HRAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL21484651 | 0.77 | NPC1 (0.63) | LTA4HRAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL3038954 | 0.75 | NPC1 (0.67) | LTA4HRAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL27039686 | 0.73 | NPC1 (0.45) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30745779 | 0.73 | NPC1 (0.45) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL18172012 | 0.73 | ALDH1A1 (0.50) | LTA4HALDH1A1MAPT | |
| SCHEMBL24358000 | 0.72 | KCNN1 (0.58) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL24358076 | 0.72 | NPC1 (0.60) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022087326-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | CELGENE CORPORATION (US) | 2022-04-28 | — | — | WO | disclosed |