Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | TPO | P07202 | 1/20 | 0.41 |
| ▸ | EPX | P11678 | 1/20 | 0.41 |
| ▸ | LPO | P22079 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 4/20 | 0.39 |
| ▸ | CDK7 | P50613 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28749827 | 0.82 | HTT (0.43) | ALDH1A1MAPTMEN1USP2KMT2A | |
| SCHEMBL29706051 | 0.82 | HTT (0.43) | ALDH1A1MAPTMEN1USP2KMT2A | |
| SCHEMBL507036 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL30699249 | 0.78 | KDM4E (0.40) | KDM4EHSD17B10MPOTPOEPX | |
| SCHEMBL625665 | 0.78 | KDM4E (0.40) | KDM4EHSD17B10MPOTPOEPX | |
| SCHEMBL23634063 | 0.77 | NCF1 (0.47) | ALDH1A1MAPTMPOTPOEPX | |
| SCHEMBL506299 | 0.77 | CHRNB2 (0.42) | ALDH1A1MAPTKMT2ACACNA1GCACNA1H | |
| SCHEMBL17099993 | 0.77 | ALDH1A1 (0.41) | ALDH1A1MAPTL3MBTL1KDM4EPIK3CD | |
| SCHEMBL29700311 | 0.77 | ALDH1A1 (0.41) | ALDH1A1MAPTL3MBTL1KDM4EPIK3CD | |
| SCHEMBL11183436 | 0.76 | MAOB (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114552005-A | Electrolyte and application thereof | 湖北亿纬动力有限公司 | 2022-05-27 | — | — | CN | claimed |
| US-12384773-B2 | Thiazole compounds and methods of use thereof | ARCUS BIOSCIENCES, INC. (US) | 2025-08-12 | — | — | US | disclosed |
| US-20250145606-A1 | THIAZOLE COMPOUNDS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2025-05-08 | — | — | US | disclosed |
| WO-2025096979-A1 | THIAZOLE COMPOUNDS AS KIT INHIBITORS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2025-05-08 | — | — | WO | disclosed |
| CN-113754679-B | Substituted pyrimidinediones and their use | 广东东阳光药业有限公司 | 2023-04-07 | — | — | CN | disclosed |
| US-20230027929-A1 | MrgprX2 Antagonists and Uses Thereof | DERMIRA, INC. | 2023-01-26 | — | — | US | disclosed |
| EP-4054570-A1 | MRGPRX2 ANTAGONISTS AND USES THEREOF | Dermira, Inc (US) | 2022-09-14 | — | — | EP | disclosed |
| CN-114901280-A | MrgprX2 antagonists and uses thereof | 德米拉公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-114552005-A | Electrolyte and application thereof | 湖北亿纬动力有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-113754679-A | Substituted pyrimidinediones and their use | 广东东阳光药业有限公司 | 2021-12-07 | — | — | CN | disclosed |
| US-20180105509-A1 | AMINO-SUBSTITUTED HETEROCYCLIC DERIVATIVES AS SODIUM CHANNEL INHIBITORS | ALMIRALL, S.A. (ES) | 2018-04-19 | — | — | US | disclosed |
| EP-3286178-A1 | AMINO-SUBSTITUTED HETEROCYCLIC DERIVATIVES AS SODIUM CHANNEL INHIBITORS | Almirall S.A. (ES) | 2018-02-28 | — | — | EP | disclosed |
| WO-2016170009-A1 | AMINO-SUBSTITUTED HETEROCYCLIC DERIVATIVES AS SODIUM CHANNEL INHIBITORS | ALMIRALL, S.A. (ES) | 2016-10-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12384773-B2 | Thiazole compounds and methods of use thereof | TPMT, CYP11B2, ABAT | ALDH1A1 198/4885MAPT 1247/4885L3MBTL1 1803/4885 |
| US-20180105509-A1 | AMINO-SUBSTITUTED HETEROCYCLIC DERIVATIVES AS SODIUM CHANNEL INHIBITORS | SCN7A, SCN1A, SCN1B | ALDH1A1 1764/4885MAPT 3214/4885L3MBTL1 4234/4885 |
| US-20250145606-A1 | THIAZOLE COMPOUNDS AND METHODS OF USE THEREOF | TPMT, CYP11B2, ABAT | ALDH1A1 198/4885MAPT 1247/4885L3MBTL1 1803/4885 |
| US-20230027929-A1 | MrgprX2 Antagonists and Uses Thereof | MRGPRX2, MRGPRX1, MRGPRX4 | ALDH1A1 2645/4885MAPT 4178/4885L3MBTL1 4533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.