Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 4/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29620239 | 1.00 | KMT2A (0.47) | KMT2AMEN1NPC1HTTRAB9A | |
| SCHEMBL30300235 | 0.82 | AR (0.44) | KMT2AMEN1NPC1HTTRAB9A | |
| SCHEMBL29287831 | 0.81 | KMT2A (0.47) | KMT2AMEN1NPC1HTTRAB9A | |
| SCHEMBL2362495 | 0.81 | TSHR (0.47) | KMT2AMEN1HTTMAPTKDM4E | |
| SCHEMBL29583963 | 0.81 | TSHR (0.47) | KMT2AMEN1HTTMAPTKDM4E | |
| SCHEMBL488979 | 0.81 | KMT2A (0.56) | KMT2AMEN1NPC1HTTRAB9A | |
| SCHEMBL28307395 | 0.81 | MAPT (0.49) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL22531728 | 0.81 | KDM4E (0.42) | KMT2AMEN1NPC1HTTRAB9A | |
| SCHEMBL486746 | 0.80 | KMT2A (0.46) | KMT2AMEN1NPC1HTTRAB9A | |
| SCHEMBL7589287 | 0.80 | KMT2A (0.46) | KMT2AMEN1NPC1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022084562-A1 | STRUCTURALLY RIGID DIANIONS FOR METAL CATALYSIS | Universität Zürich (CH) | 2022-04-28 | — | — | WO | disclosed |