Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29287831 | 0.84 | KMT2A (0.47) | KMT2AMEN1NPC1HTTRAB9A | |
| SCHEMBL488979 | 0.84 | KMT2A (0.56) | KMT2AMEN1NPC1HTTRAB9A | |
| SCHEMBL7589287 | 0.83 | KMT2A (0.46) | KMT2AMEN1NPC1HTTRAB9A | |
| SCHEMBL4352323 | 0.82 | MEN1 (0.46) | KMT2AMEN1GRM6ARHPGD | |
| SCHEMBL1936278 | 0.81 | PRNP (0.49) | KMT2AMEN1NPC1HTTRAB9A | |
| SCHEMBL17828206 | 0.81 | MEN1 (0.44) | KMT2AMEN1NPC1HTTRAB9A | |
| SCHEMBL31752732 | 0.81 | MEN1 (0.44) | KMT2AMEN1NPC1HTTRAB9A | |
| SCHEMBL29549088 | 0.81 | PRNP (0.49) | KMT2AMEN1NPC1HTTRAB9A | |
| SCHEMBL2217741 | 0.81 | TRPA1 (0.45) | KMT2AMEN1NPC1HTTRAB9A | |
| SCHEMBL257409 | 0.80 | LMNA (0.50) | KMT2AMEN1HTTRAB9ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103562189-B | Insecticidal compounds | 先正达参股股份有限公司 | 2016-11-23 | — | — | CN | disclosed |
| EP-2411384-A1 | INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108733-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2010-09-30 | — | — | WO | disclosed |