Sugi Predict

Sugi Predict / Compounds / SCHEMBL488979

SCHEMBL488979

SCHEMBL488979

CC(C)(C)OC(=O)c1ccccc1Br

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 6/20 0.56
▸ NPC1 O15118 3/20 0.56
▸ RAB9A P51151 3/20 0.56
▸ MEN1 O00255 1/20 0.56
▸ HTT P42858 1/20 0.56
▸ CASP3 P42574 1/20 0.45
▸ SENP8 Q96LD8 1/20 0.45
▸ SENP7 Q9BQF6 1/20 0.45
▸ SENP6 Q9GZR1 1/20 0.45
▸ L3MBTL1 Q9Y468 1/20 0.45
▸ MAPT P10636 4/20 0.43
▸ HPGD P15428 3/20 0.43
▸ LMNA P02545 1/20 0.43
▸ CYP1A2 P05177 1/20 0.43
▸ CYP2C19 P33261 1/20 0.43
▸ ALDH1A1 P00352 4/20 0.43
▸ GAA P10253 2/20 0.43
▸ USP2 O75604 1/20 0.43
▸ MIF P14174 1/20 0.43
▸ KDM4E B2RXH2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1784955 0.89 KMT2A (0.49) KMT2ANPC1RAB9AMEN1HTT
SCHEMBL30111657 0.86 TSHR (0.50) KMT2ANPC1RAB9AMEN1HTT
SCHEMBL109178 0.86 TSHR (0.50) KMT2ANPC1RAB9AMEN1HTT
SCHEMBL29287831 0.85 KMT2A (0.47) KMT2ANPC1RAB9AMEN1HTT
SCHEMBL4828257 0.84 KMT2A (0.46) KMT2ANPC1RAB9AMEN1HTT
SCHEMBL7589287 0.84 KMT2A (0.46) KMT2ANPC1RAB9AMEN1HTT
SCHEMBL486746 0.84 KMT2A (0.46) KMT2ANPC1RAB9AMEN1HTT
Hydrogen Peroxide SCHEMBL29048859 0.84 TSHR (0.48) KMT2ANPC1RAB9AMEN1HTT
SCHEMBL17828206 0.82 MEN1 (0.44) KMT2ANPC1RAB9AMEN1HTT
SCHEMBL31752732 0.82 MEN1 (0.44) KMT2ANPC1RAB9AMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 356 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260028482-A1 Substitution at the Central Position of Heptamethine Dyes By Aryllithium Addition for Improved Fluorophores UNIV ARKANSAS (US) 2026-01-29 — — US claimed
CN-116854631-B 4-Aryl-2-pyridone compound and preparation method thereof 安徽中医药大学 2025-04-15 — — CN claimed
CN-116854631-A 4-aryl-2-pyridone compound and preparation method thereof 安徽中医药大学 2023-10-10 — — CN claimed
CN-111334066-B 640nm excited near-infrared fluorescent dye and preparation method thereof 中国科学院大连化学物理研究所 2021-12-10 — — CN claimed
CN-111334066-A 640nm excited near-infrared fluorescent dye and preparation method thereof 中国科学院大连化学物理研究所 2020-06-26 — — CN claimed
CN-111334079-A Full-spectrum high-brightness and high-stability fluorescent dye and synthesis and application thereof 中国科学院大连化学物理研究所 2020-06-26 — — CN claimed
WO-2020124688-A1 FULL-SPECTRUM HIGH-BRIGHTNESS AND HIGH-STABILITY FLUORESCENT DYES, AND SYNTHESIS AND APPLICATION THEREOF 中国科学院大连化学物理研究所 2020-06-25 — — WO claimed
US-20260138956-A1 NOVEL COMPOUNDS AND USES THEREOF RECURSION PHARMACEUTICALS INC (US) 2026-05-21 — — US disclosed
US-20260132129-A1 4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE DERIVATIVES FOR TREATING CANCER GENESIS THERAPEUTICS INC (US) 2026-05-14 — — US disclosed
US-20260130925-A1 METHODS FOR TREATING CANCER GENESIS MOLECULAR AI INC (US) 2026-05-14 — — US disclosed
EP-4705281-A1 COMPOUNDS FOR TREATING CANCER Genesis Molecular AI, Inc. (US) 2026-03-11 — — EP disclosed
US-20260028482-A1 Substitution at the Central Position of Heptamethine Dyes By Aryllithium Addition for Improved Fluorophores UNIV ARKANSAS (US) 2026-01-29 — — US disclosed
US-20250296915-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2025-09-25 — — US disclosed
US-5252593-A Hypotensive agents, cognition activators GLAXO GROUP LIMITED (GB) 1993-10-12 — — US disclosed
WO-1993005025-A1 C-LINKED PYRAZOLE DERIVATIVES GLAXO GROUP LIMITED (GB) 1993-03-18 — — WO disclosed
EP-0514193-A1 N-linked imidazolyl-methyl benzofuran derivatives with antihypotensive activity GLAXO GROUP LIMITED (GB) 1992-11-19 — — EP disclosed
EP-0514217-A1 Antihypertensive benzofuran derivatives carrying 4-pyrazolylmethyl substituents GLAXO GROUP LIMITED (GB) 1992-11-19 — — EP disclosed
EP-0514198-A1 1H-Imidazol-1-yl-methyl benzofuran derivatives with the imidazolyl moiety being substituted by a cycloalkyl group GLAXO GROUP LIMITED (GB) 1992-11-19 — — EP disclosed
US-5068300-A BIFUNCTIONAL STILBENE COMPOUNDS CONTAINING AT LEAST ONE Z-CONFIGURATED STILBENE GROUP, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR THE PREPARATION OF POLYMERS BAYER AKTIENGESELLSCHAFT (DE) 1991-11-26 — — US disclosed
EP-0446062-A1 C-Linked pyrazole derivatives GLAXO GROUP LIMITED (GB) 1991-09-11 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260138956-A1 NOVEL COMPOUNDS AND USES THEREOF SLC10A1, NR3C2, CYP2C8 KMT2A 3898/4885NPC1 9/4885RAB9A 418/4885
US-20250296915-A1 NOVEL AMINO ACID DERIVATIVES DNPEP, BCAT1, ANPEP KMT2A 2979/4885NPC1 4280/4885RAB9A 1854/4885
US-20260132129-A1 4H-PYRIDO[1,2-A]PYRIMIDIN-4-ONE DERIVATIVES FOR TREATING CANCER PIK3R4, PIK3R1, PIK3R5 KMT2A 2156/4885NPC1 855/4885RAB9A 386/4885
US-20260130925-A1 METHODS FOR TREATING CANCER PIK3R1, PIK3R5, PIK3R2 KMT2A 2190/4885NPC1 159/4885RAB9A 274/4885
US-20260028482-A1 Substitution at the Central Position of Heptamethine Dyes By Aryllithium Addition for Improved Fluorophores KCNK5, KCNA7, KCNA4 KMT2A 1152/4885NPC1 1995/4885RAB9A 2038/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.