Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.36 |
| ▸ | GRM5 | P41594 | 3/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | AMPD2 | Q01433 | 2/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24359289 | 0.81 | NR3C2 (0.40) | NR3C2AKR1B1GRM5TRPV1 | |
| SCHEMBL17169809 | 0.78 | NISCH (0.37) | — | |
| SCHEMBL22938912 | 0.73 | PGR (0.34) | NR3C2TRPV1 | |
| SCHEMBL20345686 | 0.72 | NPY5R (0.40) | AKR1B1 | |
| SCHEMBL22482139 | 0.70 | SLC6A2 (0.51) | SLC6A2SLC6A4 | |
| SCHEMBL22938911 | 0.70 | ABCB1 (0.35) | — | |
| SCHEMBL27659846 | 0.66 | SLC6A2 (0.41) | SLC6A2SLC6A4 | |
| SCHEMBL15724661 | 0.65 | AKR1B1 (0.46) | AKR1B1 | |
| SCHEMBL18707375 | 0.63 | AKR1B1 (0.44) | NR3C2AKR1B1TRPV1 | |
| SCHEMBL3319434 | 0.62 | KCNE1 (0.44) | AKR1B1TRPV1CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022087624-A1 | COMPOUNDS AS RAS INHIBITORS AND USES THEREOF | BIOARDIS LLC (US) | 2022-04-28 | — | — | WO | disclosed |