Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | DNTT | P04053 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL183877 | 0.88 | KMT2A (0.43) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL23932135 | 0.88 | KMT2A (0.43) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL5227279 | 0.82 | NPC1 (0.33) | ALDH1A1MAPTKDM4ENPC1CASP3 | |
| SCHEMBL2476888 | 0.79 | ALDH1A1 (0.35) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL13039618 | 0.75 | NPC1 (0.41) | MEN1KMT2ANPC1CASP3RAB9A | |
| SCHEMBL4773759 | 0.74 | NPC1 (0.37) | NPC1CASP3RAB9ASENP8NLRP3 | |
| SCHEMBL31544797 | 0.73 | TLR4 (0.39) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL13823454 | 0.73 | NPC1 (0.35) | MEN1KMT2ANPC1CASP3RAB9A | |
| SCHEMBL10974043 | 0.72 | NPC1 (0.46) | GAAKMT2ANPC1CASP3RAB9A | |
| SCHEMBL7729951 | 0.70 | ALDH1A1 (0.40) | ALDH1A1MAPTDNTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022087624-A1 | COMPOUNDS AS RAS INHIBITORS AND USES THEREOF | BIOARDIS LLC (US) | 2022-04-28 | — | — | WO | disclosed |
| WO-2022087624-A1 | COMPOUNDS AS RAS INHIBITORS AND USES THEREOF | BIOARDIS LLC (US) | 2022-04-28 | — | — | WO | disclosed |