Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24145267 | 0.81 | ALDH1A1 (0.44) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL30619945 | 0.78 | HDAC7 (0.45) | ALDH1A1L3MBTL1LMNA | |
| SCHEMBL18287375 | 0.76 | ALDH1A1 (0.40) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL23463613 | 0.75 | ALDH1A1 (0.39) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL24359328 | 0.75 | KMT2A (0.41) | ALDH1A1L3MBTL1TACR1LMNA | |
| SCHEMBL5546203 | 0.75 | ALDH1A1 (0.57) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL26004981 | 0.75 | ALDH1A1 (0.57) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL28565885 | 0.74 | PTPN1 (0.47) | NPC1ALDH1A1RAB9AL3MBTL1KEAP1 | |
| Hydrogen Sulfide SCHEMBL28059716 | 0.73 | ALDH1A1 (0.55) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 | |
| SCHEMBL1532928 | 0.73 | ALDH1A1 (0.46) | NPC1ALDH1A1PLA2G1BNFKB1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220127291-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2022-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220127291-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | RER1, OCIAD2, OXSR1 | NPC1 3692/4885ALDH1A1 1214/4885PLA2G1B 2116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.